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Results for "

alkynyl group

" in MedChemExpress (MCE) Product Catalog:

32

Inhibitors & Agonists

5

Fluorescent Dyes

17

Biochemical Assay Reagents

14

Click Chemistry

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W040304
    Alkynyl Palmitic Acid
    3 Publications Verification

    Alk-C16

    PROTAC Linkers Cancer
    Alkynyl Palmitic Acid (Alk-C16) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . Alkynyl Palmitic Acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Alkynyl Palmitic Acid
  • HY-140335
    Alkynyl myristic acid
    4 Publications Verification

    PROTAC Linkers Cancer
    Alkynyl myristic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . Alkynyl myristic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Alkynyl myristic acid
  • HY-126192

    PiB; 6-OH-BTA-1

    Amyloid-β Neurological Disease
    Pittsburgh Compound B (PiB) is a blood-brain barrier-permeable, specific deposition PET tracer that binds to Aβ(1-40) fibrils with a Ki value of 678.4 nM. Through click chemical modification (a clickable Pittsburgh Compound B derivative is prepared by introducing a PEG3 linker and an alkynyl group at the 6-hydroxy site of Pittsburgh Compound B, followed by covalent conjugation with azide-labeled fluorescent dyes or affinity tags via copper-catalyzed azide-alkyne cycloaddition (CuAAC)), Pittsburgh Compound B and its conjugates can be used for fluorescence imaging, ultrastructural studies, and enrichment and characterization of Aβ complexes. Pittsburgh Compound B is applicable to Alzheimer's disease research .
    Pittsburgh Compound B
  • HY-115495

    Biochemical Assay Reagents Others
    6-Alkynyl fucose is a tool in the study of protein O-fucosylation . 6-Alkynyl fucose is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    6-Alkynyl fucose
  • HY-170528

    PROTAC Linkers Others
    DBCO-PEG3-NHS is a biochemical assay reagent, that can be used to chemically modify proteins and antibodies with an alkynyl (DBCO) or N-hydroxysuccinimide (NHS) ester group. DBCO-PEG3-NHS can be used as a linker in PROTAC synthesis or for drug delivery and the development of biosensors and diagnostic reagents .
    DBCO-PEG3-NHS
  • HY-D2161A

    Fluorescent Dye Others
    AF 594 azide (triethylamine) is an azide derivative of the red fluorescent dye AF 594, which has high fluorescence quantum yield and high photostability (maximum absorption wavelength of 586 nm, maximum emission wavelength of 613 nm). AF 594 azide (triethylamine) forms stable adducts by reaction of the azide group with alkynyl derivatives (terminal alkynes and cyclooctyne) .
    AF 594 azide triethylamine
  • HY-W1049105

    Biochemical Assay Reagents Others
    mPEG2000-Alkyne is a PEG derivative. The alkynyl group can react with azide in aqueous solution under the catalysis of monovalent copper. Polyethylene glycol derivatives can increase the solubility and stability of drugs, reduce the immunogenicity of peptides, and have good biocompatibility .
    mPEG2000-Alkyne
  • HY-D2161

    Fluorescent Dye Others
    AF 594 azide is an azide derivative of the red fluorescent dye AF 594, which has high fluorescence quantum yield and high photostability (maximum absorption wavelength of 586 nm, maximum emission wavelength of 613 nm). AF 594 azide forms stable adducts by reaction of the azide group with alkynyl derivatives (terminal alkynes and cyclooctyne). It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups .
    AF 594 azide
  • HY-D2112

    Fluorescent Dye Others
    TAMRA-PEG7-N3 is a TAMRA (HY-135640) dye derivative containing 7 PEG units. TAMRA-PEG7-N3 undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing an alkynyl group (N3). It also undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    TAMRA-PEG7-N3
  • HY-D2111

    Fluorescent Dye Others
    TAMRA-PEG2-N3 is a TAMRA (HY-135640) dye derivative containing 4 PEG units. TAMRA-PEG2-N3 undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing an alkynyl group (N3). It also undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    TAMRA-PEG2-N3
  • HY-D2911

    Biochemical Assay Reagents Metabolic Disease
    Pantetheine probe PP-3 (Compound PP-3) is an alkynyl group connector probe. Pantetheine probe PP-3 selectively enriches and maps modification sites (e.g., Ser231 on DHRS2). Pantetheine probe PP-3 is promising for research of metabolic disorders (e.g., fatty acid synthesis dysregulation) .
    Pantetheine probe PP-3
  • HY-116879

    (2E)-4-Oxo-2-nonen-8-ynal; alkynyl-4-ONE

    Exosomes Others Cancer
    4-Oxo-2-Nonenal Alkyne ((2E)-4-Oxo-2-nonen-8-ynal; alkynyl-4-ONE) is a functionalized lipid electrophile that conjugated to the exosomes via the reaction of amino and aldehyde groups. 4-Oxo-2-Nonenal Alkyne can be used in tumor exosomes determination .
    4-Oxo-2-Nonenal Alkyne
  • HY-W1049091C

    Biochemical Assay Reagents Others
    mPEG20000-Alkyne is a PEG derivative. The alkynyl group can react with azide in aqueous solution under the catalysis of monovalent copper. Polyethylene glycol derivatives can increase the solubility and stability of drugs, reduce the immunogenicity of peptides, and have good biocompatibility .
    mPEG20000-Alkyne
  • HY-174969

    Biochemical Assay Reagents Others
    Alkyne-PEG1000-Silane is a PEG derivative composed of silane, PEG, and alkynyl groups. Alkyne-PEG1000-Silane is a click chemistry reagent. It contains an Alkyne group, which can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an Azide group. The Silane group enables Alkyne-PEG1000-Silane to modify surfaces such as glass and silicon .
    Alkyne-PEG1000-Silane
  • HY-174946

    DPPE-PEG1-N3

    Biochemical Assay Reagents Others
    DPPE-PEG1-azide (DPPE-PEG1-N3) is a PEG-modified lipid containing an azide group. DPPE-PEG1-azide can undergo a copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkynyl group. It can also undergo ring strain-driven alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .
    DPPE-PEG1-azide
  • HY-174946A

    DPPE-PEG5-N3

    Biochemical Assay Reagents Others
    DPPE-PEG5-azide (DPPE-PEG5-N3) is a PEG-modified lipid containing an azide group. DPPE-PEG5-azide can undergo a copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkynyl group. It can also undergo ring strain-driven alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .
    DPPE-PEG5-azide
  • HY-W457950

    E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis Cancer
    Thalidomide-5-propargyl is a propargyl-modified Thalidomide (HY-14658), that acts as a Cereblon ligand to recruit CRBN proteins. Thalidomide-5-propargyl use alkynyl group at the end to be directly used in the synthesis of triazoles in the synthesis of PROTAC molecules, and is a key intermediate in the synthesis of PROTAC molecules based on CRBN design .
    Thalidomide-5-propargyl
  • HY-157515

    E3 Ligase Ligand-Linker Conjugates Cancer
    Thalidomide 4'-ether-PEG2-azide is a click chemistry modified cereblon (CRBN) inhibitor Thalidomide (HY-14658). Thalidomide 4'-ether-PEG2-azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkynyl groups. Thalidomide 4'-ether-PEG2-azide can be used as a ligand of E3 ubiquitin ligase and Linker conjugates (E3 Ligase Ligand-Linker Conjugates) for the synthesis of PROTACs .
    Thalidomide 4'-ether-PEG2-azide
  • HY-140875

    Drug Intermediate Others
    Propargyl-PEG3-triethoxysilane contains a triethoxysilane moiety and an alkynyl group. Propargyl-PEG3-triethoxysilane can be used for material surface modification, biological molecule labeling, immobilization, and so on.
    Propargyl-PEG3-triethoxysilane
  • HY-W1048860B

    Biochemical Assay Reagents Others
    4-Arm PEG10000-alkyne is a multi-arm PEG derivative with alkynyl groups at each end of four arms attached to a pentaerythritol core. PEG alkyne can be used for PEGylation via copper-catalyzed click chemistry with azides .
    4-Arm PEG10000-alkyne
  • HY-W1048860D

    Biochemical Assay Reagents Others
    4-Arm PEG40000-alkyne is a multi-arm PEG derivative with alkynyl groups at each end of four arms attached to a pentaerythritol core. PEG alkyne can be used for PEGylation via copper-catalyzed click chemistry with azides .
    4-Arm PEG40000-alkyne
  • HY-W1049091D

    Biochemical Assay Reagents Others
    mPEG40000-Alkyne is a PEG derivative. The alkynyl group can react with azide in aqueous solution under the catalysis of monovalent copper. Polyethylene glycol derivatives can increase the solubility and stability of drugs, reduce the immunogenicity of peptides, and have good biocompatibility .
    mPEG40000-Alkyne
  • HY-W1049091A

    Biochemical Assay Reagents Others
    mPEG5000-Alkyne is a PEG derivative. The alkynyl group can react with azide in aqueous solution under the catalysis of monovalent copper. Polyethylene glycol derivatives can increase the solubility and stability of drugs, reduce the immunogenicity of peptides, and have good biocompatibility .
    mPEG5000-Alkyne
  • HY-W1048860A

    Biochemical Assay Reagents Others
    4-Arm PEG5000-alkyne is a multi-arm PEG derivative with alkynyl groups at each end of four arms attached to a pentaerythritol core. PEG alkyne can be used for PEGylation via copper-catalyzed click chemistry with azides .
    4-Arm PEG5000-alkyne
  • HY-W1049091

    Biochemical Assay Reagents Others
    mPEG1000-Alkyne is a PEG derivative. The alkynyl group can react with azide in aqueous solution under the catalysis of monovalent copper. Polyethylene glycol derivatives can increase the solubility and stability of drugs, reduce the immunogenicity of peptides, and have good biocompatibility .
    mPEG1000-Alkyne
  • HY-W1049091B

    Biochemical Assay Reagents Others
    mPEG10000-Alkyne is a PEG derivative. The alkynyl group can react with azide in aqueous solution under the catalysis of monovalent copper. Polyethylene glycol derivatives can increase the solubility and stability of drugs, reduce the immunogenicity of peptides, and have good biocompatibility .
    mPEG10000-Alkyne
  • HY-W1049091E

    Biochemical Assay Reagents Others
    mPEG3400-Alkyne is a PEG derivative. The alkynyl group can react with azide in aqueous solution under the catalysis of monovalent copper. Polyethylene glycol derivatives can increase the solubility and stability of drugs, reduce the immunogenicity of peptides, and have good biocompatibility .
    mPEG3400-Alkyne
  • HY-W1048860C

    Biochemical Assay Reagents Others
    4-Arm PEG20000-alkyne is a multi-arm PEG derivative with alkynyl groups at each end of four arms attached to a pentaerythritol core. PEG alkyne can be used for PEGylation via copper-catalyzed click chemistry with azides .
    4-Arm PEG20000-alkyne
  • HY-174969C

    Biochemical Assay Reagents Others
    Alkyne-PEG5000-Silane is a PEG derivative composed of silane, PEG, and alkynyl groups. Alkyne-PEG5000-Silane is a click chemistry reagent. It contains an Alkyne group, which can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an Azide group. The Silane group enables Alkyne-PEG5000-Silane to modify surfaces such as glass and silicon .
    Alkyne-PEG5000-Silane
  • HY-174969A

    Biochemical Assay Reagents Others
    Alkyne-PEG2000-Silane is a PEG derivative composed of silane, PEG, and alkynyl groups. Alkyne-PEG2000-Silane is a click chemistry reagent. It contains an Alkyne group, which can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an Azide group. The Silane group enables Alkyne-PEG2000-Silane to modify surfaces such as glass and silicon .
    Alkyne-PEG2000-Silane
  • HY-174969B

    Biochemical Assay Reagents Others
    Alkyne-PEG3400-Silane is a PEG derivative composed of silane, PEG, and alkynyl groups. Alkyne-PEG3400-Silane is a click chemistry reagent. It contains an Alkyne group, which can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an Azide group. The Silane group enables Alkyne-PEG3400-Silane to modify surfaces such as glass and silicon .
    Alkyne-PEG3400-Silane
  • HY-173578

    Biochemical Assay Reagents Others
    N-(2-Poc-ethyl)betulin amide is a triterpenoid with antiviral and antitumor activities. N-(2-Poc-ethyl)betulin amide contains a Poc (prop-2-yn-1-yloxycarbonyl) alkynyl protecting group, which allows for bioorthogonal reactions (such as click chemistry) and is used for targeted delivery and fluorescent labeling .
    N-(2-Poc-ethyl)betulin amide

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