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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
anionic lipid
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "anionic lipid" in MCE Product Catalog:
3
3 Cited Publications
Synonyms: Dioleoylphosphatidylglycerol sodium
2
2 Cited Publications
Synonyms: 18:1 PA sodium salt
Cat. No.: HY-P0311
CAS No.: 184776-51-0
Cat. No.: HY-148009
CAS No.: 2260669-35-8
Synonyms: 16:0-18:1 Cardiolipin sodium
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Cardiolipin (16:0/18:1/16:0/18:1) (16:0-18:1 Cardiolipin) sodium is a di-saturated mitochondrial-specific anionic phospholipid sodium salt containing the long-chain fatty acid palmitic acid (HY-N0830) and the monounsaturated fatty acid oleic acid (HY-N1446). Cardiolipin (16:0/18:1/16:0/18:1) sodium undergoes in-source fragmentation via diglyceride (DG)-H2O fragment formation and (DG-H2O) fragment loss pathways. Cardiolipin (16:0/18:1/16:0/18:1) sodium can be used in the synthesis of lipid nanodiscs for application in in situ mass spectrometry .
Cat. No.: HY-W440986
CAS No.: 321595-13-5
Synonyms: DSPS sodium
Distearoylphosphatidylserine sodium is an anionic phospholipid with stearic acid tails (18:0) and contains a carboxylic acid (COOH) and amine (NH2) in their head group. It has been used in the preparation of lipid-mixing vesicles, liposome, or artificial membrane. Due to the medium size of fatty acid chain, DLPS is used to form thinner membranes/walls.
Cat. No.: HY-N6711
CAS No.: 57749-43-6
Cat. No.: HY-W714524
CAS No.: 321863-21-2
Synonyms: 16:0-18:1 PS (POPS)
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1-Palmitoyl-2-oleoyl-sn-glycero-3-PS sodium (16:0-18:1 PS (POPS)) is an anionic phosphatidylserine phospholipid with 16:0 (palmitoyl) and 18:1 (oleoyl) acyl chains. It serves as a component of biomimetic inner plasma membrane models and membrane vesicles for hemostatic response studies. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PS sodium regulates membrane electrical properties by forming tethered bilayer lipid membranes. It enhances the stability of sHDL particles without altering the cholesterol efflux capacity of sHDL. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PS sodium acts synergistically with phosphatidylcholine to support prothrombin activation. It serves as a component of the 4:1 POPC/POPS binary lipid bilayer model. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PS sodium is applicable to research related to atherosclerosis .
Cat. No.: HY-P0311A
Cat. No.: HY-W725309
CAS No.: 384833-24-3
Synonyms: 1-Stearoyl-2-oleoyl-sn-glycero-3-phosphate sodium
Cat. No.: HY-P11430
CAS No.: 290360-66-6
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Cat. No.: HY-W590676
CAS No.: 63988-20-5
Synonyms: TMCL diammonium
Tetramyristoylcardiolipin (TMCL) is an anionic lipid. Tetramyristoylcardiolipin can be used to study cell membrane function and drug delivery .
Cat. No.: HY-W440985
CAS No.: 208757-51-1
Synonyms: 1,2-dilauroyl-sn-glycero-3-phospho-L-serine
DLPS is an anionic phospholipid with lauric acid tails (12:0) and contains a carboxylic acid (COOH) and amine (NH2) in their head group. It has been used in the preparation of lipid-mixing vesicles, liposome, or artificial membrane. Due to the medium size of fatty acid chain, DLPS is used to form thinner membranes/walls.
Cat. No.: HY-P10536
CAS No.: 1802175-40-1
Cat. No.: HY-142982
CAS No.: 81490-05-3
Cat. No.: HY-W339758
CAS No.: 321883-64-1
Synonyms: 1,2-Didecanoyl-sn-glycero-3-phosphate sodium
Cat. No.: HY-P11353
CAS No.: 117138-19-9
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Cat. No.: HY-111915R
CAS No.: 108392-02-5
Synonyms: 18:1 PA sodium salt (Standard)
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1,2-Dioleoyl-sn-glycero-3-phosphate sodium salt (Standard) is the analytical standard of 1,2-Dioleoyl-sn-glycero-3-phosphate (sodium salt) (HY-111915). This product is intended for research and analytical applications. 1,2-Dioleoyl-sn-glycero-3-phosphate sodium salt (18:1 PA sodium salt) is an anionic lipid that can be used to prepare liposomes, micelles and artificial membranes .
Cat. No.: HY-185588
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Anionic Liposomes (DOPG, 10mM) is a Phosphatidylglycerol (PG)-based-100% DOPG formulation. Anionic Liposomes (DOPG, 10mM) can be used for drug delivery and lipid-protein interactions.
Cat. No.: HY-185587
Anionic Liposomes (DOPG:DOPC (90:10 molar ratio, 10 mM)) is a type of artificial lipid vesicle with strong negative charge (Liposome), composed of 90% DOPG (HY-142980) and 10% DOPC. DOPG is a phosphatidylglycerol composed of unsaturated fatty acids (oleoyl groups), providing negative charges and membrane fluidity. DOPC acts as a neutral matrix lipid, mainly used to maintain the integrity and appropriate fluidity of the lipid bilayer, and does not change the net charge itself.
Cat. No.: HY-L251
95 compounds
Ionizable lipids are a class of specialized, functional lipid molecules with pH-sensitive charge characteristics. They are primarily divided into two major categories: ionizable cationic lipids and ionizable anionic lipids, though the term typically specifies ionizable cationic lipids within the biomedical field. Structurally, these lipids consist of an ionizable hydrophilic headgroup, a biodegradable linker, and hydrophobic tails. Their primary application is serving as the key delivery vehicle in lipid nanoparticles (LNPs) to encapsulate negatively charged nucleic acid macromolecules, such as mRNA vaccines, siRNA therapeutics, and CRISPR gene-editing components. In a physiological, neutral environment, they remain electrically neutral to minimize systemic toxicity and prolong circulation time. Upon entering the acidic microenvironment of cellular endosomes, however, they undergo protonation to become positively charged, thereby inducing membrane fusion and enabling the highly efficient intracellular release of the nucleic acid cargo. Consequently, they serve as the technological cornerstone for bringing nucleic acid therapies into clinical application.
To accelerate the translational process of cutting-edge nucleic acid drugs, MCE has meticulously constructed an ionizable lipid compound library containing 95 high-performance molecules, aiming to provide researchers and pharmaceutical professionals with a high-throughput, multi-dimensional lipid screening platform.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
