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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
apoB-100
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "apoB-100" in MCE Product Catalog:
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5
5 Cited Publications
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3
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Mipomersen sodium (ISIS 301012) is an antisense oligonucleotide inhibitor of apolipoprotein B (apoB). Mipomersen has anti-HCV effect and reduces the infectivity of the HCV. Mipomersen sodium can be used for the research of homozygous familial hypercholesterolemia (HoFH) .
Synonyms: LY3473329
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Muvalaplin (LY3473329) is an orally active, selective small molecule inhibitor of lipoprotein (a) (Lp (a)) that disrupts the initial non-covalent interaction between apo(a) and apoB100, preventing the disulphide bond and Lp(a)
formation. Muvalaplin reduces the levels of Lp (a) in transgenic mice and in cynomolgus monkeys .
Category:
Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields
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Cat. No.: HY-W588264
CAS No.: 10468-90-3
Synonyms: 3-Monoiodothyronine
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3-Iodo-L-thyronine (3-Monoiodothyronine) is a thyroid hormone metabolite. 3-iodo-L-thyronine can bind to apolipoprotein B-100 (apoB-100) .
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LSN3353871 is an orally active inhibitor of lipoprotein (a) (Lp (a)) formation, with Kd values of 756 nM (apo (a) KIV8), 605 nM (apo (a) KIV7-8), and 423 nM (apo (a) KIV5-8), respectively, and an IC50 of 1.69 μM against apo (a) KIV5-8. LSN3353871 reduces circulating Lp (a) levels in transgenic mice and cynomolgus monkeys. LSN3353871 can be used in the research of atherosclerotic cardiovascular disease and calcific aortic valve disease .
Cat. No.: HY-112540AR
CAS No.: 3483-11-2
Cat. No.: HY-RS24199
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Apob Rat Pre-designed siRNA Set A contains three designed siRNAs for Apob gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P7524
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: apoB; Lipoprotein B; Apolipoprotein B; apoB Protein; Apolipoprotein B-100; Apo B-100; apoB-100; apoB-48; Apolipoprotein B (Including Ag(X) Antigen); LDLCQ4; Alternative Protein apoB; FCHL2; Apolipoprotein B48; FLDB
Cat. No.: HY-RS00833
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APOB Human Pre-designed siRNA Set A contains three designed siRNAs for APOB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P88961A
Synonyms: apoB48R; apoB100R
Cat. No.: HY-RS17734
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Apob Mouse Pre-designed siRNA Set A contains three designed siRNAs for Apob gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
