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Mipomersen sodium 

Cat. No.: HY-108764
Handling Instructions

Mipomersen (sodium) is a second-generation 20-base phosphorothioate ASO targeted to human apoB-100.

For research use only. We do not sell to patients.

Mipomersen sodium Chemical Structure

Mipomersen sodium Chemical Structure

CAS No. : 629167-92-6

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Mipomersen (sodium) is a second-generation 20-base phosphorothioate ASO targeted to human apoB-100[1][2].

In Vitro

Mipomersen predominantly distributes to the liver and decreases the production of apoB-100, the primary structural protein of the atherogenic lipoproteins including low density lipoprotein (LDL), thereby reducing plasma LDL-cholesterol and apoB-100 concentrations[2].
Apolipoprotein (apo) B, a large amphipathic protein, plays a fundamental role in human lipoprotein metabolism. ApoB-100 is also a ligand for LDL receptor-mediated endocytosis of LDL by cells[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Room temperature in continental US; may vary elsewhere.


Please store the product under the recommended conditions in the Certificate of Analysis.

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