1 Result for "

dFdC

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "dFdC" in MCE Product Catalog:

Cat. No.: HY-178451
Target:  

Apoptosis

Research Areas:  

Cancer

NQO1-responsive prodrug is a prodrug of Gemcitabine (dFdC) (HY-17026) with anti-cancer effect. NQO1-responsive prodrug remains stable in plasma and liver/intestinal S9 fractions, releasing dFdC in an NQO1-dependent manner. NQO1-responsive prodrug induces S-phase arrest and apoptosis. NQO1-responsive prodrug inhibits tumor growth in an A549 xenograft mouse model. NQO1-responsive prodrug can be used for breast and non-small cell lung cancer (NSCLC) research .
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