7 Results for "

desmosterol

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "desmosterol" in MCE Product Catalog:

6
6 Cited Publications
Cat. No.: HY-113224
CAS No.: 313-04-2
Purity:  ≥98.0%
Desmosterol is a cholesterol-like molecule. In the Bloch pathway of cholesterol biosynthesis, Desmosterol is a direct precursor of cholesterol. As an endogenous metabolite, Desmosterol is used to study cholesterol metabolism . Desmosterol is an LXR activator and SREBP inhibitor, which can suppress macrophage inflammasome activation and prevent vascular inflammation and atherosclerosis. A reduction in Desmosterol promotes the production of mitochondrial reactive oxygen species (ROS) in macrophages and pyrin domain-dependent inflammasome activation of NLRP3. Desmosterol holds potential for research in inflammation, metabolism, and cardiovascular diseases .
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3
3 Cited Publications
Cat. No.: HY-143228
CAS No.: 2143952-36-5
Purity:  99.80%
SH-42 is a potent and selective inhibitor of human Δ 24-dehydrocholesterol reductase (DHCR24), with an IC50 of 42 nM. SH-42 can lead to a significant increase in plasma desmosterol levels of mice .
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Cat. No.: HY-114298
CAS No.: 1715-86-2
Category:  

Lipids

Target:  

Endogenous Metabolite

7-Dehydro desmosterol is a sterol and an intermediate in cholesterol biosynthesis, which is found in the marine diatom Pseudo-nitzschia multistriata and the nervous system of rodents .
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Cat. No.: HY-113224S
CAS No.: 1246298-67-8
Purity:  99.38%
Desmosterol-d6 is the deuterium labeled Desmosterol. Desmosterol is a molecule similar to cholesterol. Desmosterol is the immediate precursor of cholesterol in the Bloch pathway of cholesterol biosynthesis. Desmosterol, as an endogenous metabolite, used to study cholesterol metabolism .
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Cat. No.: HY-113224R
CAS No.: 313-04-2
Desmosterol (Standard) is the analytical standard of Desmosterol. This product is intended for research and analytical applications. Desmosterol is a cholesterol-like molecule. In the Bloch pathway of cholesterol biosynthesis, Desmosterol is a direct precursor of cholesterol. As an endogenous metabolite, Desmosterol is used to study cholesterol metabolism [1]. Desmosterol is an LXR activator and SREBP inhibitor, which can suppress macrophage inflammasome activation and prevent vascular inflammation and atherosclerosis. A reduction in Desmosterol promotes the production of mitochondrial reactive oxygen species (ROS) in macrophages and pyrin domain-dependent inflammasome activation of NLRP3. Desmosterol holds potential for research in inflammation, metabolism, and cardiovascular diseases [1][2][3].
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Cat. No.: HY-146823S
CAS No.: 2260669-31-4
Desmosterol ester-d6 is deuterium labeled Desmosterol ester.
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Cat. No.: HY-181462
Target:  

Drug Derivative

Research Areas:  

Others

Desmosteryl linoleate is an ester formed by Desmosterol (HY-113224) and Linoleic acid (HY-N0729) .
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