Desmosterol-d6
Based on 1 Customer Validation
Desmosterol-d6 is the deuterium labeled Desmosterol. Desmosterol is a molecule similar to cholesterol. Desmosterol is the immediate precursor of cholesterol in the Bloch pathway of cholesterol biosynthesis. Desmosterol, as an endogenous metabolite, used to study cholesterol metabolism.
For research use only. We do not sell to patients.
- Purity: 99.38%
- CAS No.: 1246298-67-8
- Formula: C27H38D6O
- Molecular Weight:390.67
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1246298-67-8
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Unlabeled Cas 313-04-2
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Appearance Solid
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Molecular Weight 390.67
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Formula C27H38D6O
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Color White to off-white
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SMILES
C[C@@]12[C@](CC[C@]2([H])[C@H](C)CC/C=C(C([2H])([2H])[2H])/C([2H])([2H])[2H])([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(C[C@H](CC4)O)=CC3)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMF : ≥ 50 mg/mL (127.99 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMF | 1 mM | 2.5597 mL | 12.7985 mL | 25.5971 mL | 63.9926 mL |
| 5 mM | 0.5119 mL | 2.5597 mL | 5.1194 mL | 12.7985 mL | |
| 10 mM | 0.2560 mL | 1.2799 mL | 2.5597 mL | 6.3993 mL | |
| 15 mM | 0.1706 mL | 0.8532 mL | 1.7065 mL | 4.2662 mL | |
| 20 mM | 0.1280 mL | 0.6399 mL | 1.2799 mL | 3.1996 mL | |
| 25 mM | 0.1024 mL | 0.5119 mL | 1.0239 mL | 2.5597 mL | |
| 30 mM | 0.0853 mL | 0.4266 mL | 0.8532 mL | 2.1331 mL | |
| 40 mM | 0.0640 mL | 0.3200 mL | 0.6399 mL | 1.5998 mL | |
| 50 mM | 0.0512 mL | 0.2560 mL | 0.5119 mL | 1.2799 mL | |
| 60 mM | 0.0427 mL | 0.2133 mL | 0.4266 mL | 1.0665 mL | |
| 80 mM | 0.0320 mL | 0.1600 mL | 0.3200 mL | 0.7999 mL | |
| 100 mM | 0.0256 mL | 0.1280 mL | 0.2560 mL | 0.6399 mL |