31 Results for "

human CD20

" in MedChemExpress (MCE) Product Catalog:
Products (31)

31 Results for "human CD20" in MCE Product Catalog:

14
14 Cited Publications
Cat. No.: HY-P9913
CAS No.: 174722-31-7
Synonyms: Anti-human CD20 type I, Chimeric Antibody; HSDB 7455; IDEC-C2B8
Rituximab is an anti-CD20 chimeric monoclonal antibody used for research of certain autoimmune diseases and cancer.
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P9910
CAS No.: 949142-50-1
Synonyms: GA101; Anti-human CD20 type II, humanized Antibody

Target:  

CD20

Research Areas:  

Cancer

Obinutuzumab (GA101) a Type II CD20 humanized IgG1 monoclonal antibody in development for non-Hodgkin lymphoma.
loading...
    loading...
Cat. No.: HY-P9961
CAS No.: 679818-59-8
Synonyms: GSK1841157; OMB-157

Target:  

CD20

Research Areas:  

Cancer

Ofatumumab is a fully human anti-CD20 monoclonal antibody that induces antibody-dependent cell-mediated cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC) in CD20-expressing B lymphocytes. Ofatumumab has strong lytic activity against CD20-positive B lymphocytes and eliminates CD20-positive tumor cells through ADCC and CDC. Ofatumumab is particularly effective against drug-resistant cells with low CD20 expression and can be applied to the research of chronic lymphocytic leukemia (CLL) .
loading...
    loading...
Cat. No.: HY-P99056
CAS No.: 1417318-27-4
Synonyms: PF 05082566

Target:  

TNF Receptor

Research Areas:  

Cancer

Utomilumab (PF 05082566) is a fully human IgG2 agonist monoclonal antibody that selectively binds to 4-1BB/CD137. Utomilumab can be used in the research of tumors such as follicular and other CD20 + non-Hodgkin lymphomas .
loading...
    loading...
Cat. No.: HY-P99326
CAS No.: 192391-48-3
Synonyms: Anti-human CD20 Recombinant Antibody; V10XA53

Target:  

CD20

Research Areas:  

Cancer

Tositumomab (Anti-Human CD20 Recombinant Antibody) is a mouse-derived IgG2a monoclonal antibody, targeting to human CD20. Tositumomab can deplete B cells. Tositumomab can be used for the research of cancer, such as lymphoma .
loading...
    loading...
Cat. No.: HY-P99038
CAS No.: 1801338-64-6
Synonyms: REGN1979

Target:  

CD20 CD3

Research Areas:  

Cancer

Odronextamab is a stable humanized IgG4 CD20 × CD3 bispecific antibody that binds to CD3 on T cells and CD20 on B cells, triggering anti-tumor activity. Odronextamab is expected to be used in oncology research .
loading...
    loading...
Cat. No.: HY-P99776
CAS No.: 2138442-31-4
Synonyms: XmAb-13676

Target:  

CD20 CD3

Research Areas:  

Cancer

Plamotamab (XmAb-13676) is a human bispecific antibody (bsAb) that binds CD3 and CD20. Plamotamab recruits cytotoxic T cells to kill CD20 + expressing tumor cells. Plamotamab induces a mild hematologic reaction (MR), and results in tumor regression in vivo .
loading...
    loading...
Cat. No.: HY-P990138

Target:  

CD20

Anti-Monkey/Human CD20 Antibody (2H7) is a mouse-derived IgG2b κ type antibody inhibitor, targeting to monkey/human CD20. Anti-Monkey/Human CD20 Antibody (2H7) specifically depletes B cells. Anti-Monkey/Human CD20 Antibody (2H7) can be used for the researches of inflammation and metabolic disease, such as diabetes and experimental autoimmune encephalomyelitis .
loading...
    loading...
Cat. No.: HY-P99952
CAS No.: 2249927-04-4
Synonyms: SCT400
Ripertamab (SCT400) is a recombinant human-mouse chimeric anti-CD20 IgG1κ monoclonal antibody. As an immunomodulator, ripertamab reduces the levels of pathogenic autoantibodies, alleviates immune complex deposition, and blocks the antigen-presenting function of cells. Ripertamab depletes CD20-positive cells. Ripertamab can induce infusion-related reactions, pulmonary toxicity, neutropenia and thrombocytopenia. Ripertamab is applicable to research related to non-Hodgkin's lymphoma, primary membranous nephropathy and idiopathic membranous nephropathy .
loading...
    loading...
Cat. No.: HY-P991225

Target:  

Fc Receptor (FcR) CD20

Research Areas:  

Inflammation/Immunology Cancer

BI-1206 is a recombinant and antagonistic human monoclonal antibody targeting FcγRIIB (CD32B). BI-1206 can block CD20 internalization induced by Rituximab (HY-P9913) itself or combined with others including Ibrutinib (HY-10997), Venetoclax (HY-15531), and CHOP. BI-1206 can enhance or recover the activity of Rituximab or other anti-CD20 monoclonal antibodies. BI-1206 has cytolytic activity against malignant B cells. BI-1206 can be studied for cancer research such as mantle cell lymphoma (MCL) .
loading...
    loading...
Cat. No.: HY-P990599

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Ibritumomab is a mouse antibody expressed in CHO, targeting CD20/MS4A1. Ibritumomab is equipped with a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for Ibritumomab can refer to Human IgG1 kappa, Isotype Control (HY-P99001).
loading...
    loading...
Cat. No.: HY-P991547
CAS No.: 922534-56-3

Target:  

CD20 Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

Anti-CD20 Antibody (mAb 1.5.3) is a fully human IgG1 anti-CD20 antibody. Anti-CD20 Antibody (mAb 1.5.3) evokes enhanced pro-apoptotic activity in vitro. Anti-CD20 Antibody (mAb 1.5.3) mediated both complement-dependent cytotoxicity and antibody-dependent cellular cytotoxicity. Anti-CD20 Antibody (mAb 1.5.3) demonstrates enhanced anti-tumor activity in various tumor xenograft models. Anti-CD20 Antibody (mAb 1.5.3) produces a superior B-cell depletion profile in lymph node organs and bone marrow in a primate pharmacodynamic model. Anti-CD20 Antibody (mAb 1.5.3) can be studied in research for B-cell maglignancies .
loading...
    loading...
Cat. No.: HY-P990350

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Anti-CD20 Antibody is a humanized antibody expressed in CHO that targets CD20/MS4A1. The Anti-CD20 Antibody is composed of huIgG1 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for Anti-CD20 Antibody can refer to Human IgG2 kappa, Isotype Control (HY-P99002).
loading...
    loading...
Cat. No.: HY-P991545

Target:  

CD20

Research Areas:  

Cancer

BVX20 is a human monoclonal antibody that binds to CD20. BVX20 can kill B-cells through recruiting the immune system. BVX20 can be studied in research for relapsed or chemotherapy-resistant follicular B-cell NHL and CD20-positive diffuse large B-cell NHL .
loading...
    loading...
Cat. No.: HY-P990954
CAS No.: 2850355-94-9
Synonyms: IMM-0306

Target:  

CD47 CD20

Research Areas:  

Cancer

Amulirafusp alfa (IMM-0306) is a fusion protein of CD20 monoclonal antibody (mAb) with the CD47 binding domain of SIRPα, with human CD20 Kd 2.45 nM and human CD47 Kd 4.91 nM. Amulirafusp alfa binds to CD20 and CD47 on B cells, engages FcɣR, blocks CD47-SIRPα interaction, activates macrophages, NK cells, and complement cascade, mediates phagocytosis and cytotoxicity, inhibits apoptosis of Jurkat-CSR cells, reverses IL-16 tumor-promoting effects, and binds human/cynomolgus CD47 but not mouse/rat CD47. Amulirafusp alfa can be used for the research of hematological malignancies, relapsed or refractory CD20-positive B-cell non-Hodgkin’s lymphoma, relapsed or refractory B-cell non-Hodgkin lymphoma, and activated B-cell-like diffuse large B-cell lymphoma .
loading...
    loading...
Cat. No.: HY-P991546

Target:  

CD20

Research Areas:  

Cancer

MEDI-552 is a human IgG monoclonal antibody targeting CD20/membrane-spanning 4-domains subfamily A member 1 (MS4A1) .
loading...
    loading...
Cat. No.: HY-P990054
Synonyms: IGN-002

Target:  

CD20

Research Areas:  

Cancer

Eramkafusp Alfa is a human IgG1 antibody targeting the mouse B lymphocyte CD20 antigen MS4A1 .
loading...
    loading...
Cat. No.: HY-P991903

Target:  

CD20

Research Areas:  

Cancer

PSB102 is a humanized Fc-enhanced IgG1 monoclonal antibody directed against the human B-cell-specific cell surface antigen and tumor-associated antigen CD20 .
loading...
    loading...
Cat. No.: HY-P992466

Target:  

CD20

Research Areas:  

Cancer

SM09 is an anti-human CD20 antibody.
loading...
    loading...
Cat. No.: HY-P992144
CAS No.: 3062698-53-4
Synonyms: RO-7121932

Research Areas:  

Others

Zareprumig is a human monoclonal antibody targeting CD20/MS4A1&CD71/TFRC .
loading...
    loading...