192391-48-3
192391-48-3
Chemical Structure
Tositumomab
Synonym(s): Anti-Human CD20 Recombinant Antibody; V10XA53
- CAS No.: 192391-48-3
- Formula:N/A
- Molecular Weight:(147.298 kDa)
SMILES: [Tositumomab]
Biological Activity: Tositumomab (Anti-Human CD20 Recombinant Antibody) is a mouse-derived IgG2a monoclonal antibody, targeting to human CD20. Tositumomab can deplete B cells. Tositumomab can be used for the research of cancer, such as lymphoma[1][2].
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Tositumomab | 96.00% | Tositumomab (Anti-Human CD20 Recombinant Antibody) is a mouse-derived IgG2a monoclonal antibody, targeting to human CD20. Tositumomab can deplete B cells. Tositumomab can be used for the research of cancer, such as lymphoma. | ||||||||||||||||||||
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References
- [1]. Havlena GT, et al. Cure of Micrometastatic B-Cell Lymphoma in a SCID Mouse Model Using 213Bi-Anti-CD20 Monoclonal Antibody. J Nucl Med. 2023 Jan;64(1):109-116. [Content Brief]
- [2]. Beers SA, et al. Type II (tositumomab) anti-CD20 monoclonal antibody out performs type I (rituximab-like) reagents in B-cell depletion regardless of complement activation. Blood. 2008 Nov 15;112(10):4170-7. [Content Brief]
Keywords
