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Ripertamab

(Synonyms: SCT400)
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Based on 1 Customer Validation

Ripertamab (SCT400) is a recombinant human-mouse chimeric anti-CD20 IgG1κ monoclonal antibody. As an immunomodulator, ripertamab reduces the levels of pathogenic autoantibodies, alleviates immune complex deposition, and blocks the antigen-presenting function of cells. Ripertamab depletes CD20-positive cells. Ripertamab can induce infusion-related reactions, pulmonary toxicity, neutropenia and thrombocytopenia. Ripertamab is applicable to research related to non-Hodgkin's lymphoma, primary membranous nephropathy and idiopathic membranous nephropathy.

For research use only. We do not sell to patients.

  • Purity : ≥99.0%
  • CAS No.: 2249927-04-4
  • Molecular Weight:144.56 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Ripertamab
  • Experimental Validation Results for Ripertamab
  • Experimental Validation Results for Ripertamab
  • Ripertamab Chemical Structure
    Ripertamab Chemical Structure
CAS No.: 2249927-04-4
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Ripertamab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized CD20/MS4A1 Protein-VLP, Human (HEK293, HY-P78543) can bind Ripertamab. The EC50 for this effect is 4.506 ng/mL.

  • 1/16

    Flow Cytometry analysis of Raji cells labelling CD20 (red) with Ripertamab (HY-P99952). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Ripertamab Chemical Structure
    1/16
  • Ripertamab
  • Immobilized CD20/MS4A1 Protein-VLP, Human (HEK293, HY-P78543) can bind Ripertamab. The EC50 for this effect is 4.506 ng/mL.
  • Flow Cytometry analysis of Raji cells labelling CD20 (red) with Ripertamab (HY-P99952). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).