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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
human NTPDase1
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "human NTPDase1" in MCE Product Catalog:
Cat. No.: HY-173447
CAS No.: 344402-39-7
8-BuS-AMP is a NTPDase1 inhibitor and a CD73/CD39 inhibitor, with an IC50 of 35 μM and a Ki value of 0.292 μM against human NTPDase1; its Ki values against human CD73 and CD39 are 1.19 μM and 0.847 μM, respectively. 8-BuS-AMP binds to the substrate-binding pockets of NTPDase1 and CD73 to effectively block the conversion of ATP and AMP to adenosine, thereby enhancing the activation and proliferation of human peripheral T lymphocytes. 8-BuS-AMP possesses excellent enzymatic hydrolysis resistance and metabolic stability, resists hydrolysis by multiple NTPDase subtypes, and shows no activity against P2Y1 and P2Y12 receptors. 8-BuS-AMP can be used in purinergic signaling pathway and cancer-related studies .
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
PSB-06126 is a selective nucleoside triphosphate diphosphohydrolase (NTPDase) inhibitor, with the Ki values of 0.33 μM for rat NTPDase 1, 19.1 μM for NTPDase 2 and 2.22 μM for NTPDase 3, respectively. PSB-06126 acts on human NTPDase 3 with an IC50 value of 7.76 μM and a Ki value of 4.39 μM .
Cat. No.: HY-143288
CAS No.: 2883147-47-3
NTPDase2-IN-1 is a non-competitive, selective NTPDase2 inhibitor, with an IC50 of 0.04 μM against h-NTPDase2 and an IC50 of 2.27 μM against h-NTPDase8. NTPDase2-IN-1 is applicable for cancer-related research .
Cat. No.: HY-183701
Research Areas:
CD73/NTPDase1-IN-1 is a dual NTPDase1 and CD73 inhibitor, with IC50 values of 2.20 μM and 1.70 μM against human targets, respectively. CD73/NTPDase1-IN-1 can be used in the research of diseases such as inflammation, immunity and tumors .
Cat. No.: HY-P75417
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ENTPD1; ATP Diphosphohydrolase; Prev. CD39; Ecto-ATPase 1; ATPDase; CD39 Antigen; NTPDase-1; Ecto-Apyrase; SPG64; NTPDase1; Nucleoside Triphosphate Diphosphohydrolase 1; ATP-DPH; Lymphoid Cell Activation Antigen; Alternative Protein ENTPD1; Ecto-ATP Dipho
Species:
Source:
Cat. No.: HY-P704307
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: ENTPD1; ATP Diphosphohydrolase; Prev. CD39; Ecto-ATPase 1; ATPDase; CD39 Antigen; NTPDase-1; Ecto-Apyrase; SPG64; NTPDase1; Nucleoside Triphosphate Diphosphohydrolase 1; ATP-DPH; Lymphoid Cell Activation Antigen; Alternative Protein ENTPD1; Ecto-ATP Dipho
Cat. No.: HY-P704468
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ENTPD1; ATP Diphosphohydrolase; Prev. CD39; Ecto-ATPase 1; ATPDase; CD39 Antigen; NTPDase-1; Ecto-Apyrase; SPG64; NTPDase1; Nucleoside Triphosphate Diphosphohydrolase 1; ATP-DPH; Lymphoid Cell Activation Antigen; Alternative Protein ENTPD1; Ecto-ATP Dipho
Cat. No.: HY-P704469
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ENTPD1; ATP Diphosphohydrolase; Prev. CD39; Ecto-ATPase 1; ATPDase; CD39 Antigen; NTPDase-1; Ecto-Apyrase; SPG64; NTPDase1; Nucleoside Triphosphate Diphosphohydrolase 1; ATP-DPH; Lymphoid Cell Activation Antigen; Alternative Protein ENTPD1; Ecto-ATP Dipho
Cat. No.: HY-P704470
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ENTPD1; ATP Diphosphohydrolase; Prev. CD39; Ecto-ATPase 1; ATPDase; CD39 Antigen; NTPDase-1; Ecto-Apyrase; SPG64; NTPDase1; Nucleoside Triphosphate Diphosphohydrolase 1; ATP-DPH; Lymphoid Cell Activation Antigen; Alternative Protein ENTPD1; Ecto-ATP Dipho
Cat. No.: HY-P705299
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ENTPD1; ATP Diphosphohydrolase; Prev. CD39; Ecto-ATPase 1; ATPDase; CD39 Antigen; NTPDase-1; Ecto-Apyrase; SPG64; NTPDase1; Nucleoside Triphosphate Diphosphohydrolase 1; ATP-DPH; Lymphoid Cell Activation Antigen; Alternative Protein ENTPD1; Ecto-ATP Dipho
Cat. No.: HY-103263R
CAS No.: 1052089-16-3
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
PSB-06126 (Standard) is the analytical standard of PSB-06126 (HY-103263). This product is intended for research and analytical applications. PSB-06126 is a selective nucleoside triphosphate diphosphohydrolase (NTPDase) inhibitor, with the Ki values of 0.33 μM for rat NTPDase 1, 19.1 μM for NTPDase 2 and 2.22 μM for NTPDase 3, respectively. PSB-06126 acts on human NTPDase 3 with an IC50 value of 7.76 μM and a Ki value of 4.39 μM .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
