CD73/NTPDase1-IN-1
CD73/NTPDase1-IN-1 is a dual NTPDase1 and CD73 inhibitor, with IC50 values of 2.20 μM and 1.70 μM against human targets, respectively. CD73/NTPDase1-IN-1 can be used in the research of diseases such as inflammation, immunity and tumors.
For research use only. We do not sell to patients.
- Formula: C20H19F3N4O2S2
- Molecular Weight:468.52
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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NTPDase1 2.2 μM (IC50) |
CD73/NTPDase1-IN-1 (Compound 5n) is a dual NTPDase1 and CD73 inhibitor. Ectonucleotidases can regulate extracellular purinergic signaling pathways by converting adenosine triphosphate into adenosine; these pathways play a key role in immune responses, inflammatory reactions, and tumor progression[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 468.52
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Formula C20H19F3N4O2S2
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SMILES
O=S(N1C2=CC=C(/C=N/NC(NC3=C(C(F)(F)F)C=CC=C3)=S)C=C2C=C1)(CCC)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)