PSB-06126 (Standard)
PSB-06126 (Standard) is the analytical standard of PSB-06126 (HY-103263). This product is intended for research and analytical applications. PSB-06126 is a selective nucleoside triphosphate diphosphohydrolase (NTPDase) inhibitor, with the Ki values of 0.33 μM for rat NTPDase 1, 19.1 μM for NTPDase 2 and 2.22 μM for NTPDase 3, respectively. PSB-06126 acts on human NTPDase 3 with an IC50 value of 7.76 μM and a Ki value of 4.39 μM.
For research use only. We do not sell to patients.
- CAS No.: 1052089-16-3
- Formula: C24H15N2NaO5S
- Molecular Weight:466.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 1052089-16-3
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Molecular Weight 466.44
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Formula C24H15N2NaO5S
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SMILES
O=S(C(C(N)=C1C2=O)=CC(NC3=C4C=CC=CC4=CC=C3)=C1C(C5=C2C=CC=C5)=O)(O[Na])=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Younis Baqi, et al. Ecto-nucleotidase inhibitors: recent developments in drug discovery. Mini Rev Med Chem. 2015;15(1):21-33. [Content Brief]
[2]. Amelie Fiene, et al. Fluorescence polarization immunoassays for monitoring nucleoside triphosphate diphosphohydrolase (NTPDase) activity. Analyst. 2015 Jan 7;140(1):140-8. [Content Brief]
[3]. J B Noronha-Matos, et al. Mesenchymal Stem Cells Ageing: Targeting the "Purinome" to Promote Osteogenic Differentiation and Bone Repair. J Cell Physiol. 2016 Sep;231(9):1852-61. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)