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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
human OX1R
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "human OX1R" in MCE Product Catalog:
12
12 Publications Verification
Synonyms: Hypocretin-1 (human, rat, mouse)
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12
12 Publications Verification
Cat. No.: HY-106224B
Purity: 99.93%
Synonyms: Hypocretin-1 (human, rat, mouse) acetate
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12
12 Publications Verification
Cat. No.: HY-106224A
Purity: 97.13%
Synonyms: Hypocretin-1 (human, rat, mouse) TFA
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Cat. No.: HY-147403S
CAS No.: 1637681-55-0
Synonyms: JNJ-61393215
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JNJ-54717793, as a brain penetrant, is an orally active, selective and high affinity orexin-1 receptor (OX1R) antagonist (plasma EC50=85 ng/mL). The Ki values of JNJ-54717793 for hOX1R (human OX1R) and hOX2R are 16 nM and 700 nM, respectively. JNJ-54717793 is a potent compound of anxiety disorders .
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MK-3697 is an orally active orexin 2 receptor (OX2R) antagonist, with an IC50 value of 16 nM and a Ki value of 1.1 nM against human OX2R. MK-3697 blocks the wake-promoting OX2R signaling pathway, reduces active wake time, and increases slow-wave sleep and rapid eye movement sleep time in mice, rats and dogs. MK-3697 can be used for research on insomnia .
Cat. No.: HY-106224AS1
Synonyms: Hypocretin-1-13C18,15N3 (human, rat, mouse) TFA
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Cat. No.: HY-P3867
CAS No.: 1129545-33-0
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Cat. No.: HY-184879
CAS No.: 1628320-31-9
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Orexin 1 receptor modulator-1 is a highly potent and selective modulator of the orexin 1 receptor (OX1R), with a Ki value of 4 nM for both rat OX1R and human OX1R, and a Ki value of 767 nM for human OX2R. Orexin 1 receptor modulator-1 can be used in studies related to the orexin signaling pathway and the nervous system .
Cat. No.: HY-P703944
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HCRTR1; Hypocretin Receptor Type 1; Hypocretin Receptor 1; Orexin Receptor Type 1; ORXR1; Orexin Receptor 1; OX1R; OX-1-R; OXR1; OX1-R; Orexin/Hypocretin Receptor Type 1; OX1R; Hypocretin (Orexin) Receptor 1
Cat. No.: HY-106224AS
Synonyms: Hypocretin-1-13C6,15N (human, rat, mouse) TFA
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
