Orexin 1 receptor modulator-1
Orexin 1 receptor modulator-1 is a highly potent and selective modulator of the orexin 1 receptor (OX1R), with a Ki value of 4 nM for both rat OX1R and human OX1R, and a Ki value of 767 nM for human OX2R. Orexin 1 receptor modulator-1 can be used in studies related to the orexin signaling pathway and the nervous system.
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- CAS. Nr.: 1628320-31-9
- Formel: C23H18F4N4O2
- Molecular Weight:458.41
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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OX1 Receptor 4 nM (Ki, human, mice) |
human OX2R 767 nM (Ki) |
Orexin 1 receptor modulator-1 (compound 27) (0.1 nM-10 μM; 60 min) binds to rat OX1R and human OX1R in competitive radioligand binding assays, with a Ki value of 4 nM for both, and binds to human OX2R with a Ki value of 767 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 1628320-31-9
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Molecular Weight 458.41
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Formel C23H18F4N4O2
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SMILES
O=C(C1=C(C2=NC=CC=N2)C(F)=CC=C1)N3[C@]4([H])[C@@H](C[C@@](C3)([H])C4)OC5=CC=C(C=N5)C(F)(F)F
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Orexin 1 receptor modulator-1 Related Classifications
HY-184879 Related Classifications
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