2. Search Result
Search Result
Results for "

human telomerase

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

1

Recombinant Proteins

2

Antibodies

2

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-12854
    Imetelstat

    GRN163L

    		 Telomerase Apoptosis Cardiovascular Disease Cancer
    Imetelstat (GRN163L) is a 13-mer oligonucleotide and competitive Telomerase inhibitor. Imetelstat binds with high affinity to the template region of the RNA component of human telomerase. Imetelstat induces Apoptosis. Imetelstat is capable of selectively eliminating myelofibrosis hematopoietic stem cells. Imetelstat leads to the loss of a cancer cell's ability to maintain telomere length, resulting in the inhibition of cell proliferation .
    Imetelstat
  • HY-15523A
    Braco-19 trihydrochloride
    5 Publications Verification

    		 DNA/RNA Synthesis CMV Infection Cancer
    Braco-19 trihydrochloride is a potent telomerase/telomere inhibitor, preventing the capping and catalytic action of telomerase. Braco-19 acts as G-quadruplex (GQ) binding ligand, stabilizing G-quadruplexes formation at the 3V telomeric DNA overhang and produce rapid senescence or selective cell death. Braco-19 is also a HAdV virus replication inhibitor .
    Braco-19 trihydrochloride
  • HY-105067A
    Tertomotide hydrochloride

    GV-1001 hydrochloride

    		 Telomerase Neurological Disease
    Tertomotide (GV1001) hydrochloride is peptide vaccine consists a 16-aa human telomerase reverse transcriptase (hTERT) sequence. Tertomotide hydrochloride shows neuroprotective. Tertomotide hydrochloride has the potential for the research of Alzheimer's disease .
    Tertomotide hydrochloride
  • HY-175103
    Guanine-2'-deoxy-β-L-ribofuranosyl-5'-O-triphosphate sodium

    β-L-dGTP sodium; L-2'-Deoxyguanosine 5'-triphosphate sodium; 2’-Deoxy-L-GTP sodium

    		 Telomerase Others
    Guanine-2'-deoxy-β-L-ribofuranosyl-5'-O-triphosphate (sodium) is an isomer of dGTP and an inhibitor of telomerase with a Ki of 15 μM for human enzyme .
    Guanine-2'-deoxy-β-L-ribofuranosyl-5'-O-triphosphate sodium
  • HY-174537
    Human TERT mRNA

    		mRNA Cancer
    Human TERT mRNA encodes the human telomerase reverse transcriptase (TERT) protein, a catalytic subunit of the enzyme telomerase, which, together with the telomerase RNA component (TERC), comprises the most important unit of the telomerase complex.
    Human TERT mRNA
  • HY-122092
    FJ-5002

    		Telomerase Cancer
    FJ-5002 is a telomerase inhibitor with an IC50 of 2 μM. FJ-5002 can induce telomere shortening, increased chromosomal abnormalities, and senescence/crisis-like features in the human leukemia cell line U937. FJ-5002 exhibits antitumor activity and can be used in the study of cancer .
    FJ-5002
  • HY-179480
    G-quadruplex ligand 4

    		Drug Derivative G-quadruplex Apoptosis Telomerase Ras Bcl-2 Family Cancer
    G-quadruplex ligand 4 is a chromenone derivative and is a human telomerase reverse transcriptase (hTERT) G4 ligand. G-quadruplex ligand 4 downregulates hTERT expression and exhibits notable cytotoxicity towards triple-negative breast cancer (TNBC) cell lines. G-quadruplex ligand 4 can cause S/G2 cell cycle arrest and induce apoptosis. G-quadruplex ligand 4 downregulates the expression of hTERT, KRAS, and BCL-2. G-quadruplex ligand 4 can be used for the research of TNBC .
    G-quadruplex ligand 4

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: