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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
52 Results for "
hydratase
" in MedChemExpress (MCE) Product Catalog:
Products (52)
52 Results for "hydratase" in MCE Product Catalog:
20
20 Publications Verification
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Fumarate hydratase-IN-1 (compound 2) is a cell-permeable fumarate hydratase inhibitor. Fumarate hydratase-IN-1 has antiproliferative activity against several cancer cell lines with a mean IC50 of 2.2 μM .
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1 Cited Publications
Cat. No.: HY-W020215
CAS No.: 99-14-9
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1 Cited Publications
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Fumarate hydratase-IN-2 sodium salt (compound 3) is a cell-permeable and competitive fumarate hydratase inhibitor (Ki=4.5 μM) with nutrient-dependent cytotoxicity .
Cat. No.: HY-134136A
CAS No.: 324518-20-9
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Cat. No.: HY-153141
CAS No.: 2035018-15-4
MP-1 is a potent Fumarate hydratase-dependent hit. MP-1 engages an array of functional cysteines, including one lying in the Zn-finger domain of the tRNA methyltransferase enzyme TRMT1. MP-1 causes fumarate hydratase-dependent synthetic lethality in a metastatic hereditary leiomyomatosis and renal cell carcinoma cell line .
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3-(1-Cyanoethyl)benzoic acid (DF2107Y) is a benzoic acid that can be used to screen cobalt containing nitrile hydratases (NHases) .
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Cat. No.: HY-W020215R
CAS No.: 99-14-9
Cat. No.: HY-134136B
CAS No.: 799812-82-1
Synonyms: S-Octanoate-CoA triammonium; S-Octanoate-coenzyme A triammonium
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Octanoyl coenzyme A triammonium is an enoyl-CoA hydratase binder. Octanoyl coenzyme A triammonium binds to the active site of enoyl-CoA hydratase, occupies the binding pocket for the fatty acid tail of the enzyme's substrate, and induces a conformational shift in a flexible protein loop via its longer octanoyl chain, forming an open channel leading to the inter-trimer gap .
Cat. No.: HY-E70612
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Nitril hydratase can convert nitriles to the corresponding higher-value amides under mild conditions. Nitril hydratase is an important catalyst .
Cat. No.: HY-100005AR
CAS No.: 2070009-45-7
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Fumarate hydratase-IN-2 (sodium salt) (Standard) is the analytical standard of Fumarate hydratase-IN-2 (sodium salt) (HY-100005A). This product is intended for research and analytical applications. Fumarate hydratase-IN-2 sodium salt (compound 3) is a cell-permeable and competitive fumarate hydratase inhibitor (Ki=4.5 μM) with nutrient-dependent cytotoxicity .
Cat. No.: HY-E72080
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Acetylene hydratase (EC 4.2.1.112) is a lyase that can convert acetaldehyde into acetylene and H2O.
Cat. No.: HY-E72081
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Acetylenecarboxylate hydratase (EC 4.2.1.27) is a lyase that can convert 3-oxopropanoate into propynoate and H2O.
Cat. No.: HY-E71050
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Fumarate Hydratase, Human (EC 4. 2. 1. 2) catalyzes the reversible hydration of fumarate to malate. In its mitochondrial form, fumarate is involved in the Krebs Cycle, while the cytosolic form is involved in amino acid metabolism.
Cat. No.: HY-E71665
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3-Cyanoalanine hydratase (EC 4.2.1.65) belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds.
Cat. No.: HY-E70919
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Nitrile hydratase, Sinorhizobium meliloti (EC 4.2.1.84) is a mononuclear iron or non-corrinoid cobalt enzyme that catalyse the hydration of diverse nitriles to their corresponding amides.
Cat. No.: HY-E70919A
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Nitrile hydratase, Rhodopseudomonas palustris (EC 4.2.1.84) is a mononuclear iron or non-corrinoid cobalt enzyme that catalyse the hydration of diverse nitriles to their corresponding amides.
Cat. No.: HY-E70919B
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Nitrile hydratase, Rhodococcus erythropolis (EC 4.2.1.84) is a mononuclear iron or non-corrinoid cobalt enzyme that catalyse the hydration of diverse nitriles to their corresponding amides.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
