1. Metabolic Enzyme/Protease
  2. Mitochondrial Metabolism
  3. Fumarate hydratase-IN-2 sodium salt

Fumarate hydratase-IN-2 sodium salt 

Cat. No.: HY-100005A Purity: 98.05%
Handling Instructions

Fumarate hydratase-IN-2 sodium salt (compound 3) is a cell-permeable and competitive fumarate hydratase inhibitor (Ki=4.5 μM) with nutrient-dependent cytotoxicity .

For research use only. We do not sell to patients.

Fumarate hydratase-IN-2 sodium salt Chemical Structure

Fumarate hydratase-IN-2 sodium salt Chemical Structure

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 407 In-stock
Estimated Time of Arrival: December 31
1 mg USD 180 In-stock
Estimated Time of Arrival: December 31
5 mg USD 420 In-stock
Estimated Time of Arrival: December 31
10 mg USD 600 In-stock
Estimated Time of Arrival: December 31
25 mg USD 1200 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1920 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Fumarate hydratase-IN-2 sodium salt (compound 3) is a cell-permeable and competitive fumarate hydratase inhibitor (Ki=4.5 μM) with nutrient-dependent cytotoxicity [1].

IC50 & Target

Ki: 4.5 μM (Fumarate hydratase)[1]

Molecular Weight

440.47

Formula

C₂₅H₂₅N₂NaO₄

SMILES

O=C(O[Na])[[email protected]]1([[email protected]](CC(NC)=O)C2=O)C(N2CC(C=C3)=CC=C3C4=CC=CC=C4)=CCCC1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 10.66 mg/mL (24.20 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2703 mL 11.3515 mL 22.7030 mL
5 mM 0.4541 mL 2.2703 mL 4.5406 mL
10 mM 0.2270 mL 1.1352 mL 2.2703 mL
*Please refer to the solubility information to select the appropriate solvent.
References

Purity: 98.05%

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Fumarate hydratase-IN-2Mitochondrial MetabolismInhibitorinhibitorinhibit

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Product Name:
Fumarate hydratase-IN-2 sodium salt
Cat. No.:
HY-100005A
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