7 Results for "

iminosugar

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "iminosugar" in MCE Product Catalog:

9
9 Cited Publications
Cat. No.: HY-13005
CAS No.: 53185-12-9
Purity:  98.97%
Synonyms: D-Fagomine
Fagomine is a mild glycosidase inhibitor. The Ki of the iminosugar Fagomine is 4.8 μM, 39 μM, and 70 μM for Amyloglucosidase (A.niger), β-Glucosidase (bovine), and Isomaltase (yeast), respectively.
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3
3 Cited Publications
Cat. No.: HY-U00160
CAS No.: 615253-61-7
Synonyms: MON-​DNJ; UV4
Target:  

Flavivirus Dengue Virus

Research Areas:  

Infection

SP187 is a host-targeted iminosugar with activity against filovirus infections in vitro and in vivo. SP187 is active against influenza and dengue in vivo.
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Cat. No.: HY-129411
CAS No.: 441061-33-2
Purity:  98.60%
Synonyms: ACT-519276; OGT2378
Research Areas:  

Metabolic Disease

Sinbaglustat (OGT2378) is a dual inhibitor of glucosylceramide synthase (GCS) and non-lysosomal glucosyl ceramidase (GBA2). Sinbaglustat is an orally available N-alkyl iminosugar that crosses the blood-brain barrier. Sinbaglustat can be used for the research of central neurodegenerative diseases associated with lysosomal dysfunctions .
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Cat. No.: HY-14829F
CAS No.: 202979-51-9
Synonyms: 5-epi-Isofagomine
Target:  

Glycosidase

Research Areas:  

Metabolic Disease

L-Afegostat (5-epi-Isofagomine) is a glycosidase inhibitor. L-Afegostat is an iminosugar that can be used for the synthesis of carbohydrates. L-Afegostat shows enzyme inhibition to β-Glucosidase with an Ki of 30 μM .
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Cat. No.: HY-178202
CAS No.: 2734265-58-6
Target:  

Glycosidase

Research Areas:  

Metabolic Disease

5-C-phenethyl-DNJ is a selective α-glucosidase GAA inhibitor, with its Ki value for rhGAA being 0.81 μM. 5-C-phenethyl-DNJ exhibits extremely high selectivity for GANAB, GBA1, and GBA2. 5-C-phenethyl-DNJ can be used for the study of Pompe disease .
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Cat. No.: HY-150723
CAS No.: 2857098-72-5
Target:  

Glycosidase

Research Areas:  

Metabolic Disease

PBI-6DNJ is an orally active and potent multivalent glycosidase inhibitor. PBI-6DNJ exhibits good inhibition activity against α-glucosidase from mice, with a Ki of 0.14 μM. PBI-6DNJ exhibits good hypoglycemic activity. PBI-6DNJ can be used for type 2 diabetes research .
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Cat. No.: HY-N20714
CAS No.: 197449-09-5
(2R,3R,4R)-2-Methylpiperidine-3,4-diol is a six-membered ring iminosugar analog. Fagomine (HY-13005), an analog of (2R,3R,4R)-2-hydroxymethylpiperidine-3,4-diol, exhibits weak inhibitory activity against hepatic glycogen phosphorylase, while its isomer Isofagomine (HY-14829) possesses potent inhibitory activity. (2R,3R,4R)-2-Methylpiperidine-3,4-diol can be used in studies related to type 2 diabetes .
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