2857098-72-5
Chemical Structure
PBI-6DNJ
- CAS No.: 2857098-72-5
- Formula:C120H146N26O36
- Molecular Weight:2528.60
IUPAC Name: 5,13-bis(4-((1-(3-((2R,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl)propyl)-1H-1,2,3-triazol-4-yl)methoxy)phenoxy)-6,12-bis(4-((1-(3-((2S,3S,4S,5R)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl)propyl)-1H-1,2,3-triazol-4-yl)methoxy)phenox
InChIKey: AIZMHGROQIAGSI-IUZOMBIYSA-N
SMILES: OC[C@H]1[C@@H]([C@H]([C@@H](CN1CCCN2C=C(COC3=CC=C(C=C3)OC4=CC(C(N5CC6=CN(CCCN7[C@@H](CO)[C@@H]([C@H]([C@@H](C7)O)O)O)N=N6)=O)=C8C9=C4C%10=C%11C(C(C%12=O)=CC(OC%13=CC=C(C=C%13)OCC%14=CN(CCCN%15[C@H](CO)[C@H]([C@@H]([C@H](C%15)O)O)O)N=N%14)=C%11C9=C(C=C8C5=O)OC%16=CC=C(C=C%16)OCC%17=CN(CCCN(C[C@H]([C@@H]([C@H]%18O)O)O)[C@H]%18CO)N=N%17)=C(C=C%10OC%19=CC=C(OCC%20=CN(CCCN%21[C@H](CO)[C@H]([C@@H]([C@H](C%21)O)O)O)N=N%20)C=C%19)C(N%12CC%22=CN(CCCN%23[C@H](CO)[C@H]([C@@H]([C@H](C%23)O)O)O)N=N%22)=O)N=N2)O)O)O
Biological Activity: PBI-6DNJ is an orally active and potent multivalent glycosidase inhibitor. PBI-6DNJ exhibits good inhibition activity against α-glucosidase from mice, with a Ki of 0.14 μM. PBI-6DNJ exhibits good hypoglycemic activity. PBI-6DNJ can be used for type 2 diabetes research[1].
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PBI-6DNJ | PBI-6DNJ is an orally active and potent multivalent glycosidase inhibitor. PBI-6DNJ exhibits good inhibition activity against α-glucosidase from mice, with a Ki of 0.14 μM. PBI-6DNJ exhibits good hypoglycemic activity. PBI-6DNJ can be used for type 2 diabetes research. | |||||||||||||||||||||
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Keywords
