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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
immucillin
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "immucillin" in MCE Product Catalog:
20
20 Publications Verification
Cat. No.: HY-16210
CAS No.: 209799-67-7
Synonyms: BCX-1777; immucillin-H
Research Areas:
Forodesine (BCX-1777) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. Forodesine is a potent human lymphocyte proliferation inhibitor. Forodesine could induce apoptosis in leukemic cells by increasing the dGTP levels .
20
20 Publications Verification
Cat. No.: HY-16209
CAS No.: 284490-13-7
Synonyms: BCX-1777 hydrochloride; immucillin-H hydrochloride
Research Areas:
Forodesine hydrochloride (BCX-1777 hydrochloride) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50 values ranging from 0.48 to 1.57 nM for human, mouse, rat, monkey and dog PNP. Forodesine hydrochloride is a potent human lymphocyte proliferation inhibitor. Forodesine hydrochloride could induce apoptosis in leukemic cells by increasing the dGTP levels .
12
12 Cited Publications
Cat. No.: HY-18649
CAS No.: 222631-44-9
Synonyms: BCX4430 hydrochloride; immucillin-A hydrochloride
Target:
Research Areas:
Galidesivir (BCX4430) hydrochloride, an adenosine analog and a direct-acting antiviral agent, disrupts viral RNA-dependent RNA polymerase (RdRp) activity. Galidesivir hydrochloride is active in vitro against many RNA viral pathogens, including the filoviruses and emerging infectious agents such as MERS-CoV, SARS-CoV, and SARS-CoV-2. Galidesivir hydrochloride inhibits some negative-sense RNA viruses with EC50s ranging from ~3 to ~68 μM .
12
Target:
Research Areas:
Galidesivir (BCX4430), an adenosine analog and a direct-acting antiviral agent, disrupts viral RNA-dependent RNA polymerase (RdRp) activity. Galidesivir is active in vitro against many RNA viral pathogens, including the filoviruses and emerging infectious agents such as MERS-CoV, SARS-CoV, and SARS-CoV-2. Galidesivir inhibits some negative-sense RNA viruses with EC50s ranging from ~3 to ~68 μM .
5
5 Cited Publications
Synonyms: MTDIA; Methylthio-DADMe-immucillin A
Target:
Research Areas:
MT-DADMe-ImmA is an inhibitor of human 5'-methylthioadenosine phosphorylase (MTAP) with a Ki of 90 pM.
Cat. No.: HY-W750387
CAS No.: 209799-75-7
Target:
Research Areas:
Immucillin-G is a purine nucleoside phosphorylase (PNP) inhibitor. Immucillin-G can reduce urate levels and can be used for the research of metabolic disease, such as hyperuricemia .
Cat. No.: HY-18649B
CAS No.: 1373208-51-5
Synonyms: BCX4430 dihydrochloride; immucillin-A dihydrochloride
Target:
Research Areas:
Galidesivir (BCX4430; Immucillin-A) dihydrochloride is a broad-spectrum RNA virus inhibitor that can inhibit Ebola and yellow fever virus (Flavivirus) infections. Galidesivir has potent antiviral activity against tick-borne encephalitis virus (TBEV) and also inhibits the proliferation of many other medically important flaviviruses .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
