Galidesivir dihydrochloride
Based on 12 publication(s) in Google Scholar
Galidesivir (BCX4430; Immucillin-A) dihydrochloride is a broad-spectrum RNA virus inhibitor that can inhibit Ebola and yellow fever virus (Flavivirus) infections. Galidesivir has potent antiviral activity against tick-borne encephalitis virus (TBEV) and also inhibits the proliferation of many other medically important flaviviruses.
For research use only. We do not sell to patients.
- CAS No.: 1373208-51-5
- Formula: C11H17Cl2N5O3
- Molecular Weight:338.19
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Galidesivir dihydrochloride
More- Nucleic Acids Res. 2021 Jan 8;49(D1):D1113-D1121. [Abstract]
- Microorganisms. 2021 Mar 31;9(4):734. [Abstract]
- Antiviral Res. 2017 Jun:142:63-67. [Abstract]
- Antimicrob Agents Chemother. 2019 Feb 26;63(3):e02093-18. [Abstract]
- Viruses. 2020 Jun 10;12(6):628. [Abstract]
- Virology. 2023 Aug:585:21-31. [Abstract]
- Exp Ther Med. 2016 Sep;12(3):1812-1816. [Abstract]
- J AOAC Int. 2024 Oct 1;107(5):727-734. [Abstract]
- bioRxiv. 2025 Sep 22.
- Biomed Pharmacother. 2025 Jun:187:118104. [Abstract]
- bioRxiv. 2025 April 22.
- bioRxiv. 2025 January 29.
Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 1373208-51-5
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Molecular Weight 338.19
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Formula C11H17Cl2N5O3
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SMILES
O[C@H]1[C@H](C2=CNC3=C2N=CN=C3N)N[C@H](CO)[C@H]1O.Cl.Cl
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Synonyms
BCX4430 dihydrochloride; Immucillin-A dihydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (12)
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Journal Impact Factor
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Most Recent
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Nucleic Acids Res
COVID19 Drug Repository: text-mining the literature in search of putative COVID19 therapeutics. [Abstract]2021 Jan 8;49(D1):D1113-D1121. PMID: 33166390 -
Microorganisms
Repurposing Drugs for Mayaro Virus: Identification of EIDD-1931, Favipiravir and Suramin as Mayaro Virus Inhibitors. [Abstract]2021 Mar 31;9(4):734. PMID: 33807492 -
Antiviral Res
Antiviral activity of the adenosine analogue BCX4430 against West Nile virus and tick-borne flaviviruses. [Abstract]2017 Jun:142:63-67. PMID: 28336346 -
Antimicrob Agents Chemother
Viral RNA-Dependent RNA Polymerase Inhibitor 7-Deaza-2'- C-Methyladenosine Prevents Death in a Mouse Model of West Nile Virus Infection. [Abstract]2019 Feb 26;63(3):e02093-18. PMID: 30642926 -
Viruses
Broad-Spectrum Host-Based Antivirals Targeting the Interferon and Lipogenesis Pathways as Potential Treatment Options for the Pandemic Coronavirus Disease 2019 (COVID-19). [Abstract]2020 Jun 10;12(6):628. PMID: 32532085 -
Virology
BCX4430 inhibits the replication of rabies virus by suppressing mTOR-dependent autophagy invitro. [Abstract]2023 Aug:585:21-31. PMID: 37267717 -
Exp Ther Med
Separation of cordycepin from Cordyceps militaris fermentation supernatant using preparative HPLC and evaluation of its antibacterial activity as an NAD+-dependent DNA ligase inhibitor. [Abstract]2016 Sep;12(3):1812-1816. PMID: 27588098 -
J AOAC Int
Green and Versatile High Throughput Microwell Oxidation-Based Spectrophotometric Methods for Determination of Galidesivir in Capsules. [Abstract]2024 Oct 1;107(5):727-734. PMID: 38870529 -
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Biomed Pharmacother
Drug repositioning: Identification of potent inhibitors of NS3 protease and NS5 RdRp for control of DENV infection. [Abstract]2025 Jun:187:118104. PMID: 40300391 -
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Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Galidesivir dihydrochloride Related Classifications
HY-18649B Related Classifications
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