6 Results for "

larotrectinib

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "larotrectinib" in MCE Product Catalog:

17
17 Cited Publications
Cat. No.: HY-12866
CAS No.: 1223403-58-4
Purity:  99.95%
Synonyms: LOXO-101; ARRY-470
Target:  

Trk Receptor Apoptosis

Research Areas:  

Cancer

Larotrectinib (LOXO-101) is an ATP-competitive oral, selective inhibitor of the tropomyosin-related kinase (TRK) family receptors, with low nanomolar 50% inhibitory concentrations against all three isoforms (TRKA, B, and C).
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17
17 Cited Publications
Cat. No.: HY-12866A
CAS No.: 1223405-08-0
Purity:  98.96%
Synonyms: LOXO-101 sulfate; ARRY-470 sulfate
Target:  

Trk Receptor Apoptosis

Research Areas:  

Cancer

Larotrectinib sulfate (LOXO-101 sulfate; ARRY-470 sulfate) is an ATP-competitive oral, selective inhibitor of the tropomyosin-related kinase (TRK) family receptors, with low nanomolar 50% inhibitory concentrations against all three isoforms (TRKA, B, and C).
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Cat. No.: HY-12866R
CAS No.: 1223403-58-4
Synonyms: LOXO-101 (Standard); ARRY-470 (Standard)
Research Areas:  

Cancer

Larotrectinib (Standard) is the analytical standard of Larotrectinib. This product is intended for research and analytical applications. Larotrectinib (LOXO-101) is an ATP-competitive oral, selective inhibitor of the tropomyosin-related kinase (TRK) family receptors, with low nanomolar 50% inhibitory concentrations against all three isoforms (TRKA, B, and C).
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Cat. No.: HY-12866B
CAS No.: 1223404-68-9
Synonyms: (R)-LOXO-101; (R)-ARRY-470
Target:  

Trk Receptor

(R)-Larotrectinib is a potent TRK inhibitor with an IC50 value of 28.5 nM for TrkA. (R)-Larotrectinib can be used for researching cancer, inflammatory and certain infectious diseases
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Cat. No.: HY-12866AR
CAS No.: 1223405-08-0
Synonyms: LOXO-101 sulfate (Standard); ARRY-470 sulfate (Standard)
Research Areas:  

Cancer

Larotrectinib sulfate (Standard) is the analytical standard of Larotrectinib sulfate. This product is intended for research and analytical applications. Larotrectinib sulfate (LOXO-101 sulfate; ARRY-470 sulfate) is an ATP-competitive oral, selective inhibitor of the tropomyosin-related kinase (TRK) family receptors, with low nanomolar 50% inhibitory concentrations against all three isoforms (TRKA, B, and C).
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Cat. No.: HY-12866S1
Synonyms: LOXO-101-d4; ARRY-470-d4
Larotrectinib-d4 (LOXO-101-d4) is the deuterium labeled Larotrectinib (HY-12866). Larotrectinib (LOXO-101) is an ATP-competitive oral, selective inhibitor of the tropomyosin-related kinase (TRK) family receptors, with low nanomolar 50% inhibitory concentrations against all three isoforms (TRKA, B, and C).
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