(R)-Larotrectinib
(R)-Larotrectinib is a potent TRK inhibitor with an IC50 value of 28.5 nM for TrkA. (R)-Larotrectinib can be used for researching cancer, inflammatory and certain infectious diseases
For research use only. We do not sell to patients.
- CAS No.: 1223404-68-9
- Formula: C21H22F2N6O2
- Molecular Weight:428.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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TrkA 28.5 nM (IC50) |
Chemical Information
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CAS No. 1223404-68-9
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Molecular Weight 428.44
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Formula C21H22F2N6O2
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SMILES
O=C(N1C[C@H](O)CC1)NC2=C3N=C(N4[C@@H](C5=CC(F)=CC=C5F)CCC4)C=CN3N=C2
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Synonyms
(R)-LOXO-101; (R)-ARRY-470
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)