4 Results for "

miR-451a

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "miR-451a" in MCE Product Catalog:

hsa-miR-451a mimic
hsa-miR-451a mimic
Cat. No.: HY-R01139
Target:  

MicroRNA

Research Areas:  

Cancer

hsa-miR-451a mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
hsa-miR-451a agomir
hsa-miR-451a agomir
Cat. No.: HY-R01139A
Target:  

MicroRNA

Research Areas:  

Cancer

hsa-miR-451a agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
hsa-miR-451a inhibitor
hsa-miR-451a inhibitor
Cat. No.: HY-RI01139
Target:  

MicroRNA

Research Areas:  

Cancer

hsa-miR-451a inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
hsa-miR-451a antagomir
hsa-miR-451a antagomir
Cat. No.: HY-RI01139A
Target:  

MicroRNA

Research Areas:  

Cancer

hsa-miR-451a antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
Assay Types