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micelle encapsulation

" in MedChemExpress (MCE) Product Catalog:

28

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20

Biochemical Assay Reagents

17

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-155882

    mPEG750-NH2

    Biochemical Assay Reagents Cancer
    mPEG750-amine (mPEG750-NH2) is a chemical modification reagent for nanoparticles, capable of covalently binding to Ad-PVA to form Ad-PVA-PEG polymers. mPEG750-amine stabilizes gene delivery complexes by providing steric hindrance, reducing particle aggregation, while enhancing the water solubility and serum stability of the complex, reducing carrier cytotoxicity, and assisting in the efficient condensation of pDNA by cationic components to form nanoparticles that can be endocytosed by cells. mPEG750-amine can also be used to synthesize folate-conjugated polymer micelles for encapsulating the anticancer agent Camptothecin (HY-16560). Folate-conjugated polymer micelles are effective carriers for poorly soluble anticancer drugs, capable of avoiding macrophages and acting through folate receptor (FR)-mediated endocytosis to target tumor cells. mPEG750-amine can be applied to research in the field of non-viral gene delivery, as a component of gene delivery vectors, facilitating the safe and efficient delivery of nucleic acid drugs to target cells .
    mPEG750-amine
  • HY-W096983

    Dodecyltrimethylammonium chloride,for IPC,≥99%

    Environmental Pollutants Biochemical Assay Reagents Others
    DTAC (Dodecyltrimethylammonium chloride), for IPC, ≥99% is a quaternary ammonium cationic surfactant. DTAC, for IPC, ≥99% can form micelles in aqueous media, which interact with and encapsulate Diclofenac sodium (HY-15037) molecules; the micellization process is entropy-driven at lower temperatures and enthalpy-driven at higher temperatures .
    DTAC,for IPC,≥99%
  • HY-W440690

    Liposome Cancer
    Cholesterol-PEG2000-amine is a pegylated lipids which can be used for preparation of liposome or nanoparticle. The lipophilic moiety can encapsulate hydrophobic drugs whereas the hydrophilic PEG chain helps the overal water solubility of the micelles.
    Cholesterol-PEG2000-amine
  • HY-170851

    Apoptosis Inflammation/Immunology Cancer
    GL392 is a senolytic agent that selectively delivers the potent senolytic compound Dasatinib (HY-10181) to senescent cells. GL392 targets lipofuscin in senescent cells via the LBD domain and is linked to Dasatinib through an ester bond. Upon internalization in senescent cells, Dasatinib is released, inducing apoptosis of the senescent cells. GL392 in micelle encapsulation (mGL392) enables selective delivery to senescent cells, achieving selective senescent cell elimination in vitro and in vivo. GL392 can be used for the research of melanoma .
    GL392
  • HY-140696C

    mPEG20000-Hydroxy; Polyethylene glycol monomethyl ether 20000

    PROTAC Linkers Cancer
    m-PEG20000-OH can be used as a macroinitiator to participate in the synthesis of amphiphilic block copolymers. Nanoscale micelles can be prepared by using amphiphilic block copolymers to deliver active drugs. Paclitaxel (HY-B0015), a hydrophobic anticancer agent encapsulated in micelles, has stronger activity in killing cancer cells than free Paclitaxel. And it preferentially accumulates in tumor tissue with only limited distribution in healthy organs.
    m-PEG20000-OH
  • HY-W440706

    Liposome Cancer
    Cholesterol-PEG2000-alcohol is a pegylated lipids which can be used for preparation of liposome or nanoparticle. The lipophilic moiety can encapsulate hydrophobic drugs whereas the hydrophilic PEG chain helps the overal water solubility of the micelles. The amine can react with an activated NHS ester to form a stable amide bond.
    Cholesterol-PEG2000-alcohol
  • HY-155884

    mPEG4000-NH2

    Biochemical Assay Reagents Cancer
    mPEG4000-amine can be used to synthesize folate-conjugated polymer micelles for encapsulating anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
    mPEG4000-amine
  • HY-155880

    mPEG350-NH2

    Biochemical Assay Reagents Cancer
    mPEG350-amine can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
    mPEG350-amine
  • HY-155883

    mPEG3400-NH2

    Biochemical Assay Reagents Cancer
    mPEG3400-amine can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
    mPEG3400-amine
  • HY-172351A

    Biochemical Assay Reagents Cancer
    PEG6000-bis-amine synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent Rubitecan (HY-16560) .
    PEG6000-bis-amine
  • HY-172351B

    Biochemical Assay Reagents Cancer
    PEG10000-bis-amine synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent Rubitecan (HY-16560) .
    PEG10000-bis-amine
  • HY-172378

    Biochemical Assay Reagents Others
    Poly(styrene)-block-poly(acrylic acid) (PS:PAA 30000:2000) is a diblock copolymer used to prepare polymer micelles or vesicles and other encapsulation applications .
    Poly(styrene)-block-poly(acrylic acid) (PS:PAA 30000:2000)
  • HY-127125

    COX Inflammation/Immunology
    Diclofenac ethyl ester is the prodrug of Diclofenac (HY-15036), that is encapsulated in polymer micelles in vitro, and released with prolonged circulation time and reduced drug concentrations in the heart and kidneys in vivo .
    Diclofenac ethyl ester
  • HY-W591632

    Poly(ethylene glycol)-bis-amine (MW 1000)

    Biochemical Assay Reagents Cancer
    PEG-bis-amine (MW 1000) synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent 9-nitrocamptothecin HY-16560 (HY-16560). Folic acid-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
    PEG-bis-amine (MW 1000)
  • HY-W115607

    Poly(ethylene glycol)-bis-amine 4000

    Biochemical Assay Reagents Cancer
    PEG4000-bis-amine synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent 9-nitrocamptothecin HY-16560 (HY-16560). Folic acid-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
    PEG4000-bis-amine
  • HY-172351

    Biochemical Assay Reagents Cancer
    PEG400-bis-amine synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent Rubitecan (HY-16560) .
    PEG400-bis-amine
  • HY-W440945

    Liposome Others
    Stearic acid-PEG2000-amine is an amphiphilic PEG polymer which forms micelles in an aqueous solution. The terminal amine can react with an NHS ester to form a stable amide linkage. The aliphatic chain of stearic acid can be used to encapsulate or congregate hydrophobic therapeutic agents while the PEG chain enhances overall solubility of the polymer. Reagent grade, for research use only.
    Stearic acid-PEG2000-amine
  • HY-W590593

    Liposome Cancer
    mPEG-Cholesterol,MW 2000 is a PEG derivative which self-assembles in water to form micelle-like structure. The cholesterol tail can be used to encapsulate hydrophobic drugs while the PEG chain ehances the water solubility of the micelles.
    mPEG-Cholesterol (MW 2000)
  • HY-W591913

    Liposome Cancer
    Cholesterol-PEG2000-methoxy is a PEG derivative which self-assembles in water to form micelle-like structure. The cholesterol tail can be used to encapsulate hydrophobic drugs while the PEG chain ehances the water solubility of the micelles.
    Cholesterol-PEG2000-methoxy
  • HY-172378A

    Biochemical Assay Reagents Others
    Poly(styrene)-block-poly(acrylic acid) (PS:PAA 3,000:5,000,DDMAT terminated) is a diblock copolymer used to prepare polymer micelles or vesicles and other encapsulation applications .
    Poly(styrene)-block-poly(acrylic acid) (PS:PAA 3,000:5,000,DDMAT terminated)
  • HY-W440953

    Biochemical Assay Reagents Others
    Stearic acid-PEG1000-CH2CO2H is an amphiphilic PEG polymer which forms micelles in an aqueous solution. The aliphatic chain of stearic acid can be used to encapsulate or congregate hydrophobic therapeutic agents while the PEG chain enhances overall solubility of the polymer.
    Stearic acid-PEG1000-CH2CO2H
  • HY-W440938

    Liposome Others
    Stearic acid-PEG2000-FITC is an amphiphatic polyPEG which can self assemble to form micelles in water. The polymer can be used to encapsulate therapeutic agent. FITC is a green dye with peak absorption at 494 nm and maximum emission at 520 nm and can be used for staining biological samples or nanoparticles. FITC can be easily traced by fluorescence microscopy.
    Stearic acid-PEG2000-FITC
  • HY-W440936

    Liposome Others
    Stearic acid-PEG5000-Rhodamine is a fatty acid containing PEG polymer which can self assemble in an aqueous solution to form micelles. The polymer can be used to prepare nanoparticles for drug encapsulation. The red dye rhodamine can be easily traced by fluorescence microscopy. Rhodamine has maximum absorption at 570 nm and emission around 595 nm.
    Stearic acid-PEG5000-Rhodamine
  • HY-W440935

    Liposome Others
    Stearic acid-PEG3400-Rhodamine is a fatty acid containing PEG polymer which can self assemble in an aqueous solution to form micelles. The polymer can be used to prepare nanoparticles for drug encapsulation. The red dye rhodamine can be easily traced by fluorescence microscopy. Rhodamine has maximum absorption at 570 nm and emission around 595 nm.
    Stearic acid-PEG3400-Rhodamine
  • HY-W440902

    Biochemical Assay Reagents Others
    DSPE-PEG3400-IA is an iodoacetyll PEG lipid. The polymer can form lipid bilayer or micelles spontaneoulsy in water. The lipophilic tails can be used to encapsulate hydrophobic therapeutic agents while the hydrophilic head can be used to encapuslate hydrophilic drugs/nutrient, such as antibody, mRNA/DNA. The iodoacetyl group is reactive with thiol to produce a thioether linkage.
    DSPE-PEG3400-IA
  • HY-W440955

    Biochemical Assay Reagents Others
    Stearic acid-PEG3400-CH2CO2H is an amphiphilic PEG polymer which forms micelles in an aqueous solution. The aliphatic chain of stearic acid can be used to encapsulate or congregate hydrophobic therapeutic agents while the PEG chain enhances overall solubility of the polymer.
    Stearic acid-PEG3400-CH2CO2H
  • HY-W440956

    Biochemical Assay Reagents Others
    Stearic acid-PEG5000-CH2CO2H is an amphiphilic PEG polymer which forms micelles in an aqueous solution. The aliphatic chain of stearic acid can be used to encapsulate or congregate hydrophobic therapeutic agents while the PEG chain enhances overall solubility of the polymer.
    Stearic acid-PEG5000-CH2CO2H
  • HY-182369

    Toll-like Receptor (TLR) TNF Receptor Interleukin Related IFNAR Drug Derivative Inflammation/Immunology
    VA06 is a derivative of QS-21 (HY-101092A) that retains potent adjuvant activity while significantly reducing toxicity. VA06 self-assembles into flexible worm-like micelles with continuously elongated nanostructures and enhanced drug-loading encapsulation capacity. VA06 induces antigen-specific antibody production, enhances the secretion of TNF-α, IFN-γ and IL-2 in CD4 + and CD8 + T cells, and promotes the expression of immune-related and antiviral-related genes in mature dendritic cells. VA06 does not require liposome formulation, which simplifies production and storage processes. VA06 can be used in the research of varicella-zoster virus infection and Mycobacterium tuberculosis infection .
    VA06

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