DTAC,for IPC,≥99%
Based on 1 Customer Validation
DTAC (Dodecyltrimethylammonium chloride), for IPC, ≥99% is a quaternary ammonium cationic surfactant. DTAC, for IPC, ≥99% can form micelles in aqueous media, which interact with and encapsulate Diclofenac sodium (HY-15037) molecules; the micellization process is entropy-driven at lower temperatures and enthalpy-driven at higher temperatures.
For research use only. We do not sell to patients.
- Purity: 99.0%
- CAS No.: 112-00-5
- Formula: C15H34ClN
- Molecular Weight:263.89
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Storage:
Store at room temperature, keep dry and cool.
In solvent -80°C, 1 year , -20°C, 6 months
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
DTAC (0-1 mM) interaction with Diclofenac sodium molecules in aqueous solution causes a significant shift in the drug's characteristic UV-visible peak[1].
DTAC exhibits a linear decrease in cmc with increasing temperature in the absence of Diclofenac sodium, and a U-shaped cmc dependence with a minimum at 298.15 K in the presence of Diclofenac sodium, with corresponding thermodynamic parameters indicating entropy-driven micellisation at low temperatures and enthalpy-driven micellisation at high temperatures[1].
DTAC (0-0.010 M diclofenac sodium) shows that at 298.15 K, increasing diclofenac sodium concentration in aqueous DTAC solutions increases DTAC's cmc (from 0.0213 to 0.0261 mol kg−1) and increases its ΔGₘ0 (from -31.42 to -26.63 kJ mol−1), delaying micellisation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 112-00-5
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Appearance Solid
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Molecular Weight 263.89
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Formula C15H34ClN
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Color White to off-white
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SMILES
CCCCCCCCCCCC[N+](C)(C)C.[Cl-]
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Synonyms
Dodecyltrimethylammonium chloride,for IPC,≥99%
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature, keep dry and cool
In solvent -80°C 1 year -20°C 6 months
Solvent & Solubility
DMSO : 100 mg/mL (378.95 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 20 mg/mL (75.79 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (597 KB)
- English - EN (597 KB)
- Français - FR (597 KB)
- Deutsch - DE (597 KB)
- Norwegian - NO (597 KB)
- Español - ES (597 KB)
- Swedish - SV (597 KB)
- Italian - IT (597 KB)
- Portuguese - PT (597 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 3.7895 mL | 18.9473 mL | 37.8946 mL | 94.7364 mL |
| 5 mM | 0.7579 mL | 3.7895 mL | 7.5789 mL | 18.9473 mL | |
| 10 mM | 0.3789 mL | 1.8947 mL | 3.7895 mL | 9.4736 mL | |
| 15 mM | 0.2526 mL | 1.2632 mL | 2.5263 mL | 6.3158 mL | |
| 20 mM | 0.1895 mL | 0.9474 mL | 1.8947 mL | 4.7368 mL | |
| 25 mM | 0.1516 mL | 0.7579 mL | 1.5158 mL | 3.7895 mL | |
| 30 mM | 0.1263 mL | 0.6316 mL | 1.2632 mL | 3.1579 mL | |
| 40 mM | 0.0947 mL | 0.4737 mL | 0.9474 mL | 2.3684 mL | |
| 50 mM | 0.0758 mL | 0.3789 mL | 0.7579 mL | 1.8947 mL | |
| 60 mM | 0.0632 mL | 0.3158 mL | 0.6316 mL | 1.5789 mL | |
| DMSO | 80 mM | 0.0474 mL | 0.2368 mL | 0.4737 mL | 1.1842 mL |
| 100 mM | 0.0379 mL | 0.1895 mL | 0.3789 mL | 0.9474 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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