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  4. DTAC,for IPC,≥99%

DTAC,for IPC,≥99%  (Synonyms: Dodecyltrimethylammonium chloride,for IPC,≥99%)

Cat. No.: HY-W096983 Purity: 99.0%
COA
SDS
Handling Instructions Technical Support

DTAC (Dodecyltrimethylammonium chloride), for IPC, ≥99% is a quaternary ammonium cationic surfactant. DTAC, for IPC, ≥99% can form micelles in aqueous media, which interact with and encapsulate Diclofenac sodium (HY-15037) molecules; the micellization process is entropy-driven at lower temperatures and enthalpy-driven at higher temperatures.

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DTAC,for IPC,≥99%

DTAC,for IPC,≥99% Chemical Structure

CAS No. : 112-00-5

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Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
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DTAC,for IPC,≥99% Related Antibodies

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Description

DTAC (Dodecyltrimethylammonium chloride), for IPC, ≥99% is a quaternary ammonium cationic surfactant. DTAC, for IPC, ≥99% can form micelles in aqueous media, which interact with and encapsulate Diclofenac sodium (HY-15037) molecules; the micellization process is entropy-driven at lower temperatures and enthalpy-driven at higher temperatures[1].

In Vitro

DTAC (0-1 mM) interaction with Diclofenac sodium molecules in aqueous solution causes a significant shift in the drug's characteristic UV-visible peak[1].
DTAC exhibits a linear decrease in cmc with increasing temperature in the absence of Diclofenac sodium, and a U-shaped cmc dependence with a minimum at 298.15 K in the presence of Diclofenac sodium, with corresponding thermodynamic parameters indicating entropy-driven micellisation at low temperatures and enthalpy-driven micellisation at high temperatures[1].
DTAC (0-0.010 M diclofenac sodium) shows that at 298.15 K, increasing diclofenac sodium concentration in aqueous DTAC solutions increases DTAC's cmc (from 0.0213 to 0.0261 mol kg−1) and increases its ΔGₘ0 (from -31.42 to -26.63 kJ mol−1), delaying micellisation[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

DTAC,for IPC,≥99% Related Antibodies
Molecular Weight

263.89

Formula

C15H34ClN
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CCCCCCCCCCCC[N+](C)(C)C.[Cl-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Store at room temperature, keep dry and cool

In solvent -80°C 1 year
-20°C 6 months
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (378.95 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 20 mg/mL (75.79 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.7895 mL 18.9473 mL 37.8946 mL
5 mM 0.7579 mL 3.7895 mL 7.5789 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.0%

SDS (597 KB)

COA (240 KB) HNMR (112 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 3.7895 mL 18.9473 mL 37.8946 mL 94.7364 mL
5 mM 0.7579 mL 3.7895 mL 7.5789 mL 18.9473 mL
10 mM 0.3789 mL 1.8947 mL 3.7895 mL 9.4736 mL
15 mM 0.2526 mL 1.2632 mL 2.5263 mL 6.3158 mL
20 mM 0.1895 mL 0.9474 mL 1.8947 mL 4.7368 mL
25 mM 0.1516 mL 0.7579 mL 1.5158 mL 3.7895 mL
30 mM 0.1263 mL 0.6316 mL 1.2632 mL 3.1579 mL
40 mM 0.0947 mL 0.4737 mL 0.9474 mL 2.3684 mL
50 mM 0.0758 mL 0.3789 mL 0.7579 mL 1.8947 mL
60 mM 0.0632 mL 0.3158 mL 0.6316 mL 1.5789 mL
DMSO 80 mM 0.0474 mL 0.2368 mL 0.4737 mL 1.1842 mL
100 mM 0.0379 mL 0.1895 mL 0.3789 mL 0.9474 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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DTAC,for IPC,≥99% Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DTAC,for IPC,≥99%112-00-5Dodecyltrimethylammonium chloride,for IPC,≥99%Biochemical Assay ReagentsEnvironmental PollutantsEnvironmental Contaminantsaqueous mediaquaternary ammonium cationic surfactantmicellisation inhibitorUV-visible peakthermodynamic parameters1H NMR signalsdiclofenac sodiumInhibitorinhibitorinhibit

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