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mouse NGF

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Keap1-Nrf2 (1) Reactive Oxygen Species (ROS) (1) Small Interfering RNA (siRNA) (1) Trk Receptor (3)
By Research Areas:	Inflammation/Immunology (2) Neurological Disease (3)

Inhibitors & Agonists

Inhibitory Antibodies

Recombinant Proteins

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P991622

MNAC13	Trk Receptor	Neurological Disease Inflammation/Immunology
MNAC13 is a kind of mouse IgG1 chimeric antibody, targeting to human TrkA. MNAC13 inhibits the NGF dependent signaling pathway by specifically binding to TrkA receptors. MNAC13 has good analgesic effect and long-lasting efficacy. MNAC13 can be used for researches on inflammatory and chronic pain .

HY-RS16265

Ngf Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Ngf Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ngf gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Ngf Mouse Pre-designed siRNA Set A Ngf Mouse Pre-designed siRNA Set A

HY-116202

PACA	Keap1-Nrf2 Reactive Oxygen Species (ROS)	Neurological Disease
PACA is an enhancer of nerve growth factor-induced neurite outgrowth, enhancing nerve growth factor (NGF)-induced neurite outgrowth and attenuating 6-hydroxydopamine (6-OHDA)-induced toxicity by activating the Nrf2/HO-1 pathway. PACA has neuroprotective and neurogenic activities. PACA can be used to improve dopaminergic neuron loss and motor dysfunction in MPTP mouse models of Parkinson's disease and MPP ⁺-induced neurons .

HY-P992345

DS002	Trk Receptor	Neurological Disease
DS002 is a human monoclonal antibody targeting *NGF/bNGF, with an IC₅₀* of 6.60 nM against human *NGF, 1.98 nM against rat NGF, and 8.46 nM against mouse* *NGF. DS002 blocks NGF-TrkA* binding, interrupts pain signal transduction, inhibits TrkA-mediated downstream signaling pathways, and alters aromatic amino acid metabolic pathways. DS002 inhibits cancer cell proliferation. DS002 exerts a preventive effect on Paclitaxel-, Cisplatin- and Vincristine-induced peripheral neuropathy in rats. DS002 can be used in studies related to chronic pain and chemotherapy-induced peripheral neuropathy .

HY-P992273

Anti-NGF2 Antibody	Trk Receptor	Inflammation/Immunology
Anti-NGF2 Antibody is a monoclonal antibody targeting NGF2/NT-3. It can be used in ELISA, FACS, and functional assays. For isotype controls of Anti-NGF2 Antibody, please refer to Mouse IgG1 kappa, Isotype Control (HY-P99977).

Cat. No.	Product Name	Target	Research Area	Image

HY-P991622

MNAC13	Trk Receptor	Neurological Disease Inflammation/Immunology
MNAC13 is a kind of mouse IgG1 chimeric antibody, targeting to human TrkA. MNAC13 inhibits the NGF dependent signaling pathway by specifically binding to TrkA receptors. MNAC13 has good analgesic effect and long-lasting efficacy. MNAC13 can be used for researches on inflammatory and chronic pain .

HY-P992345

DS002	Trk Receptor	Neurological Disease
DS002 is a human monoclonal antibody targeting *NGF/bNGF, with an IC₅₀* of 6.60 nM against human *NGF, 1.98 nM against rat NGF, and 8.46 nM against mouse* *NGF. DS002 blocks NGF-TrkA* binding, interrupts pain signal transduction, inhibits TrkA-mediated downstream signaling pathways, and alters aromatic amino acid metabolic pathways. DS002 inhibits cancer cell proliferation. DS002 exerts a preventive effect on Paclitaxel-, Cisplatin- and Vincristine-induced peripheral neuropathy in rats. DS002 can be used in studies related to chronic pain and chemotherapy-induced peripheral neuropathy .

HY-P992273

Anti-NGF2 Antibody	Trk Receptor	Inflammation/Immunology
Anti-NGF2 Antibody is a monoclonal antibody targeting NGF2/NT-3. It can be used in ELISA, FACS, and functional assays. For isotype controls of Anti-NGF2 Antibody, please refer to Mouse IgG1 kappa, Isotype Control (HY-P99977).

Species:	Mouse (5)
Tag:	His (2) Tag Free (3)
Source:	HEK293 (1) CHO (1) E. coli (3)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P73317

	*Beta-NGF* Protein, Mouse (CHO)** 2 Publications Verification Beta-NGF; Beta-Nerve Growth Factor; NGF; NGFB	Mouse	CHO
	Nerve Growth Factor-β (Beta-NGF; NGF) is a neurotrophic factor that regulates neuronal survival and differentiation. NGF is also a seminal plasma protein involved in ovulation and luteinizing. NGF has potential functions in the female reproductive system to help overcome the current problem of early embryo loss. Beta-NGF Protein, Mouse (CHO) is produced by CHO cells (S122-G241), with tag free.

HY-P704363

	*Beta-NGF* Protein, Mouse (HEK293)** beta-NGF; beta-Nerve Growth Factor; NGF; NGFB	Mouse	HEK293
	Beta-NGF protein is essential for the development and maintenance of the nervous system and binds to NTRK1 and NGFR receptors to initiate signaling cascades that regulate neuronal processes. The NGF precursor proNGF acts as a ligand for the SORCS2-NGFR receptor and activates pathways affecting RAC1/2, the actin cytoskeleton, and neuronal growth. Beta-NGF Protein, Mouse (HEK293) is the recombinant mouse-derived Beta-NGF protein, expressed by HEK293, with tag free.

HY-P70530

	*Beta-NGF* Protein, Mouse (110a.a)** Beta-Nerve Growth Factor; Beta-NGF; NGF; NGFB	Mouse	E. coli
	Nerve Growth Factor-β (Beta-NGF; NGF) is a neurotrophic factor that regulates neuronal survival and differentiation. NGF is also a seminal plasma protein involved in ovulation and luteinizing. NGF has potential functions in the female reproductive system to help overcome the current problem of early embryo loss. Beta-NGF Protein, Mouse is produced by E.coli (M130-R239), with tag free.

HY-P700162AF

	*Animal-Free Beta-NGF* Protein, Mouse (His)** beta-NGF; beta-Nerve Growth Factor; NGF; NGFB	Mouse	E. coli
	Nerve Growth Factor-β (Beta-NGF; NGF) is a neurotrophic factor that regulates neuronal survival and differentiation. NGF is also a seminal plasma protein involved in ovulation and luteinizing. NGF has potential functions in the female reproductive system to help overcome the current problem of early embryo loss. Animal-Free Beta-NGF Protein, Mouse (His) is produced by E.coli, with C-terminal His-tag.This product is for cell culture use only.

HY-P70530A

	*Beta-NGF* Protein, Mouse (110a.a, His)** Beta-Nerve Growth Factor; Beta-NGF; NGF; NGFB	Mouse	E. coli
	Beta-NGF protein is essential for the development and maintenance of the nervous system and binds to NTRK1 and NGFR receptors to initiate signaling cascades that regulate neuronal processes.The NGF precursor proNGF acts as a ligand for the SORCS2-NGFR receptor and activates pathways affecting RAC1/2, the actin cytoskeleton, and neuronal growth.Beta-NGF Protein, Mouse (110a.a, His) is the recombinant mouse-derived Beta-NGF protein, expressed by E.coli , with N-6*His labeled tag.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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