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Results for "

nitroglycerin

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

4

Peptides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-101911
    5-BDBD
    4 Publications Verification

    		 P2X Receptor Neurological Disease
    5-BDBD, a potent and selective P2X4 receptor antagonist, inhibits rP2X4R-mediated currents, with an IC50 of 0.75 μM. 5-BDBD completely blocks the basal and acute hyperalgesia induced by nitroglycerin (NTG) .
    5-BDBD
  • HY-P4545
    Abz-Gly-p-nitro-Phe-Pro-OH

    		Angiotensin Receptor Others
    Abz-Gly-p-nitro-Phe-Pro-OH is the fluorescent substrate angiotensin I converting enzyme (ACE-I) with 355 nm excitation and 405 nm emission wavelengths .
    Abz-Gly-p-nitro-Phe-Pro-OH
  • HY-163733
    AKU-005

    		FAAH MAGL Neurological Disease Inflammation/Immunology
    AKU-005 is a FAAH and MAGL dual inhibitor with IC50 values of 63, 389 nM for rat and human FAAH, respectively. AKU-005 has the potential for the research of trigeminal hyperalgesia .
    AKU-005
  • HY-P4561
    H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH

    		Cathepsin Others
    H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH is a water-soluble polypeptide that can serve as a substrate for cathepsin D, pepsin and pepsinogen. H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH has potential applications in biochemical analysis .
    H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH
  • HY-P4725
    Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2

    		Fluorescent Dye Others
    Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 is a fluorogenic substrate, that can be used for the fluorescence screening assay .
    Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2
  • HY-124277
    ADM 12

    		TRP Channel Neurological Disease
    ADM 12 is a highly selective transient receptor potential ankyrin 1 (TRPA1) channel antagonist. ADM 12 blocks nitroglycerin (NTG)-induced trigeminal hyperalgesia in animal models, reducing expression of pain-related genes (c-Fos, TRPA1) and neuropeptides (CGRP, SP). ADM_12 is promising for research of migraine and neuropathic pain .
    ADM 12
  • HY-W018475
    Rizatriptan

    MK 462 free base

    		 5-HT Receptor Neurological Disease
    Rizatriptan (MK 462 free base) is an orally active 5-HT1B/5-HT1D receptor agonist, with BBB permeability. Rizatriptan exerts significant anti-migraine effects by constricting intracranial and extracranial blood vessels and inhibiting neuropeptide release. Rizatriptan exhibits species- and tissue-specific metabolic characteristics; for example, it undergoes oxidative deamination mainly by MAO-A in the liver of brown rats, so co-administration with MAO-A inhibitors is prohibited. Rizatriptan may also exacerbate nitroglycerin-induced cutaneous allodynia, prolong the duration of central sensitization, and increase anxiety-like behavior and active drug-seeking behavior in mice. Rizatriptan has been widely used in studies related to migraine and medication-overuse headache .
    Rizatriptan
  • HY-P4556
    H-Phe-Gly-His-p-nitro-Phe-Phe-Ala-Phe-OMe

    		Biochemical Assay Reagents Others
    H-Phe-Gly-His-p-nitro-Phe-Phe-Ala-Phe-OMe is a polypeptide that can be hydrolyzed by Rennin (HY-P2810). H-Phe-Gly-His-p-nitro-Phe-Phe-Ala-Phe-OMe is commonly used as a biochemical reaction reagent .
    H-Phe-Gly-His-p-nitro-Phe-Phe-Ala-Phe-OMe
  • HY-106987
    SP/W 5186

    		NO Synthase Cardiovascular Disease Inflammation/Immunology
    SP/W-5186 is a nitric oxide (NO) donor agent containing a cysteine structure. SP/W-5186 can improve cardiac function, reduce myocardial damage, protect vascular endothelial function and inhibit inflammation and oxidative stress. SP/W-5186 has the ability to inhibit oxidative damage induced by peroxynitrite (ONOO⁻). SP/W-5186 can be used in the research of myocardial ischemia-reperfusion injury .
    SP/W 5186
  • HY-B2105
    Erythrityl tetranitrate

    Tetranitrate; Nitroerythrite

    		 Drug Derivative Cardiovascular Disease
    Erythrityl tetranitrate (Tetranitrate; Nitroerythrite), a nitrate ester, is a long-acting vasodilator with properties similar to nitroglycerin. Erythrityl tetranitrate decreases the counter load of the heart and improvement of the pump function of left ventricle in an acute experiment in case of chronic cardiac insufficiency with stasis .
    Erythrityl tetranitrate
  • HY-101911R
    5-BDBD (Standard)

    		Reference Standards P2X Receptor Neurological Disease
    5-BDBD (Standard) is the analytical standard of 5-BDBD (HY-101911). This product is intended for research and analytical applications. 5-BDBD, a potent and selective P2X4 receptor antagonist, inhibits rP2X4R-mediated currents, with an IC50 of 0.75 μM. 5-BDBD completely blocks the basal and acute hyperalgesia induced by nitroglycerin (NTG) .
    5-BDBD (Standard)

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