1515855-85-2
1515855-85-2
Chemical Structure
AKU-005
- CAS No.: 1515855-85-2
- Formula:C20H21N5O
- Molecular Weight:347.41
InChIKey: DAHGNJMKRWHRFF-UHFFFAOYSA-N
SMILES: O=C(N1C=NC=N1)N2CCN(CC2)C(C3=CC=CC=C3)C4=CC=CC=C4
Biological Activity: AKU-005 is a FAAH and MAGL dual inhibitor with IC50 values of 63, 389 nM for rat and human FAAH, respectively. AKU-005 has the potential for the research of trigeminal hyperalgesia[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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AKU-005 | 99.48% | AKU-005 is a FAAH and MAGL dual inhibitor with IC50 values of 63, 389 nM for rat and human FAAH, respectively. AKU-005 has the potential for the research of trigeminal hyperalgesia. | ||||||||||||||||||||
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References
- [1]. Greco R, et al. Effects of the Dual FAAH/MAGL Inhibitor AKU-005 on Trigeminal Hyperalgesia in Male Rats. Cells. 2024 May 13;13(10):830. [Content Brief]
- [2]. Aaltonen N, et al. Piperazine and piperidine triazole ureas as ultrapotent and highly selective inhibitors of monoacylglycerol lipase. Chem Biol. 2013 Mar 21;20(3):379-90. [Content Brief]
Keywords
