1644134-60-0
1644134-60-0
Chemical Structure
ADM 12
- CAS No.: 1644134-60-0
- Formula:C11H21NO4S3
- Molecular Weight:327.48
IUPAC Name: 3-(5-(1,2-dithiolan-3-yl)pentanamido)propane-1-sulfonic acid
InChIKey: SZYIEKXYLQGLFW-UHFFFAOYSA-N
SMILES: O=S(CCCNC(CCCCC1SSCC1)=O)(O)=O
Biological Activity: ADM 12 is a highly selective transient receptor potential ankyrin 1 (TRPA1) channel antagonist. ADM 12 blocks nitroglycerin (NTG)-induced trigeminal hyperalgesia in animal models, reducing expression of pain-related genes (c-Fos, TRPA1) and neuropeptides (CGRP, SP). ADM_12 is promising for research of migraine and neuropathic pain[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
ADM 12 | 98.86% | ADM 12 is a highly selective transient receptor potential ankyrin 1 (TRPA1) channel antagonist. ADM 12 blocks nitroglycerin (NTG)-induced trigeminal hyperalgesia in animal models, reducing expression of pain-related genes (c-Fos, TRPA1) and neuropeptides (CGRP, SP). ADM_12 is promising for research of migraine and neuropathic pain. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
