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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
123 Results for "
non-receptor
" in MedChemExpress (MCE) Product Catalog:
Products (123)
123 Results for "non-receptor" in MCE Product Catalog:
12
12 Publications Verification
Synonyms: BMS 817378
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BMS 777607 (BMS 817378) is a Met-related inhibitor for c-Met, Axl, Ron and Tyro3 with IC50s of 3.9 nM, 1.1 nM, 1.8 nM and 4.3 nM, respectively, and 40-fold more selective for Met-related targets than Lck, VEGFR-2, and TrkA/B, with more than 500-fold greater selectivity versus all other receptor and non receptor kinases .
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1
1 Cited Publications
Cat. No.: HY-P73685
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PTPN1; Protein-Tyrosine Phosphatase 1B; Prev. PTP1B; Protein Tyrosine Phosphatase, Placental; Tyrosine-Protein Phosphatase non-receptor Type 1; PTP-1B; Protein Tyrosine Phosphatase non-receptor Type 1; Tyrosine-Protein Phosphatase non-receptor Type
1
1 Cited Publications
Cat. No.: HY-P71141
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PTPN6; Protein-Tyrosine Phosphatase SHP-1; Protein Tyrosine Phosphatase non-receptor Type 6; Protein-Tyrosine Phosphatase 1C; PTP-1C; SH-PTP1; HCP; Tyrosine-Protein Phosphatase non-receptor Type; SHP-1; Hematopoietic Cell Phosphatase; HCPH; Protein-Tyrosi
1
1 Cited Publications
Cat. No.: HY-P700618
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PTPN11; Protein Tyrosine Phosphatase non-receptor Type 11 Isoform 1; Prev. NS1; Tyrosine-Protein Phosphatase non-receptor Type; SH-PTP2; Protein-Tyrosine-Phosphatase; PTP2C; Noonan Syndrome 1; BPTP3; CDNA, FLJ92431; SHP-2; PTPN11 Protein; SHP2; METCDS; SH
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PROTAC PTPN2 degrader-1 is a PROTAC degrader targeting non-receptor protein tyrosine phosphatase 2 (PTPN2), with a DC50 of 18 nM in 293T cells. It exhibits an IC50 of 22 nM against PTPN2. Through highly selective degradation and inhibition of PTPN2 phosphatase, PROTAC PTPN2 degrader-1 relieves the negative regulation of the IFNγ pathway, upregulates interferon signaling, activates effector T cells, and enhances anti-tumor immunity. PROTAC PTPN2 degrader-1 can be used in melanoma-related research .
Cat. No.: HY-147316A
Purity: 99.34%
TP-5801 TFA is an orally active TNK1 (non-receptor tyrosine kinase) inhibitor (IC50=1.40 nM), and shows anti-tumor activity .
Cat. No.: HY-18316
CAS No.: 1258296-60-4
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RO495 is a potent inhibitor of non-receptor tyrosine-protein kinase 2 (TYK2 kinase) .
Cat. No.: HY-171294
CAS No.: 928316-79-4
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Protein kinase inhibitor 16 exhibits inhibitory activity against a variety of Ser/Thr kinase or receptor or non-receptor tyrosine kinase .
Cat. No.: HY-171276
CAS No.: 928316-71-6
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Anti-neuroinflammation agent 3 (Compound A.10.3) exhibits inhibitory activity against a variety of Ser/Thr kinase or receptor or non-receptor tyrosine kinase .
Cat. No.: HY-171293
CAS No.: 928317-20-8
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Protein kinase inhibitor 15 (Compound A.35.3) exhibits inhibitory activity against a variety of Ser/Thr kinase or receptor or non-receptor tyrosine kinase .
Cat. No.: HY-130631
CAS No.: 54755-93-0
SHP2-IN-5 (compound 1) is an inhibitor of SHP2 (IC50: 97 nM). SHP2 is a non-receptor protein tyrosine phosphatase associated with cell growth and proliferation. SHP2-IN-5 has the potential to inhibit cancer and SHP2-related human diseases .
Cat. No.: HY-E70834
JAK1 is a non-receptor tyrosine kinase that plays a critical role in cell signaling via type I/II cytokines and interferons (IFNs). JAK1(JH1) is a kinase domain. JAK1(JH1) Recombinant Human Active Protein Kinase is a recombinant JAK1(JH1) protein that can be used to study JAK1(JH1)-related functions .
Cat. No.: HY-E70872
TYK2 is a member of the JAK family of non-receptor tyrosine kinases that act together with signal transducer and activator of transcription (STAT) factors in mediating intracellular signal transduction. JAKs are characterized by dual kinase domain: a tyrosine kinase domain (JH1) that is preceded by a pseudokinase domain (JH2). TYK2(JH1) Recombinant Human Active Protein Kinase is a recombinant TYK2(JH1) protein that can be used to study TYK2(JH1)-related functions .
Cat. No.: HY-E70874
TYK2 is a member of the JAK family of non-receptor tyrosine kinases that act together with signal transducer and activator of transcription (STAT) factors in mediating intracellular signal transduction. JAKs are characterized by dual kinase domain: a tyrosine kinase domain (JH1) that is preceded by a pseudokinase domain (JH2). TYK2(JH2) Recombinant Human Active Protein Kinase is a recombinant TYK2(JH2) protein that can be used to study TYK2(JH2)-related functions .
Cat. No.: HY-P76557
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: PTPN12; Tyrosine-Protein Phosphatase non-receptor Type 12; Protein Tyrosine Phosphatase non-receptor Type 12; Protein-Tyrosine Phosphatase G1; PTP-PEST; Protein-Tyrosine-Phosphatase; PTPG1
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Cat. No.: HY-P71315
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SIRPB2; Protein Tyrosine Phosphatase non-receptor Type Substrate Protein; Prev. PTPNS1L3; SIRP-Beta-2; Prev. PTPN1L; Protein Tyrosine Phosphatase non-receptor Type Substrate 1-Like 3; DJ776F14.2; Protein Tyrosine Phosphatase, non-receptor Type 1-Like; Pro
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
