Search Result

Results for "

non-receptor

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adrenergic Receptor (1) Btk (2) c-Met/HGFR (1) FAK (1) Interleukin Related (1) JAK (5) Phosphatase (3) Ser/Thr Kinase (4) SHP2 (4) Src (1) STAT (2) TAM Receptor (1) TNK1 (2)
By Research Areas:	Cancer (16) Inflammation/Immunology (8) Neurological Disease (2)

Inhibitors & Agonists

Screening Libraries

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P99025

Lebrikizumab 1 Publications Verification TNX-650; MILR1444A; RG3637	Interleukin Related	Neurological Disease Inflammation/Immunology
Lebrikizumab (TNX-650) is an IgG4 humanized anti-interleukin-13 (IL-13) mAb with anti-itch effects that specifically binds to IL-13 in a non-receptor binding domain and inhibits its function. Lebrikizumab inhibits the IL-13 driven Th2 inflammatory response and blocks the signaling of IL-4Rα/IL-13Rα1. Lebrikizumab can be used for the research of asthma, atopic dermatitis and neuroinflammatory diseases .

HY-12076

BMS 777607 10+ Cited Publications BMS 817378	c-Met/HGFR TAM Receptor	Cancer
BMS 777607 (BMS 817378) is a Met-related inhibitor for c-Met, Axl, Ron and Tyro3 with IC₅₀s of 3.9 nM, 1.1 nM, 1.8 nM and 4.3 nM, respectively, and 40-fold more selective for Met-related targets than Lck, VEGFR-2, and TrkA/B, with more than 500-fold greater selectivity versus all other receptor and non receptor kinases .

HY-147316

TP-5801	STAT TNK1	Cancer
TP-5801 is an orally active TNK1 (non-receptor tyrosine kinase) inhibitor (IC₅₀=1.40 nM), and shows anti-tumor activity .

HY-131132

JAB-3068 SHP2-IN-6	SHP2 Phosphatase	Cancer
JAB-3068 (SHP2-IN-6) is a potent SHP2 inhibitor, extracted from patent WO2017211303A1, compound 7, has an IC₅₀ of 25.8 nM .

HY-131132A

JAB-3068 hydrochloride SHP2-IN-6 hydrochloride	SHP2 Phosphatase	Cancer
JAB-3068 (SHP2-IN-6) hydrochloride is a potent SHP2 inhibitor with an IC₅₀ of 25.8 nM. JAB-3068 hydrochloride is extracted from patent WO2017211303A1, compound 7 .

HY-147316A

TP-5801 TFA	STAT TNK1	Cancer
TP-5801 TFA is an orally active TNK1 (non-receptor tyrosine kinase) inhibitor (IC₅₀=1.40 nM), and shows anti-tumor activity .

HY-18316

RO495	JAK	Inflammation/Immunology
RO495 is a potent inhibitor of non-receptor tyrosine-protein kinase 2 (TYK2 kinase) .

HY-E70873

Tyk2(JH1/JH2) Recombinant Human Active Protein Kinase	JAK	Cancer
TYK2 is a member of the JAK family of non-receptor tyrosine kinases that act together with signal transducer and activator of transcription (STAT) factors in mediating intracellular signal transduction. JAKs are characterized by dual kinase domain: a tyrosine kinase domain (JH1) that is preceded by a pseudokinase domain (JH2). Tyk2(JH1/JH2) Recombinant Human Active Protein Kinase is a recombinant Tyk2(JH1/JH2) protein that can be used to study Tyk2(JH1/JH2)-related functions .

HY-117900

PF-06250112	Btk	Inflammation/Immunology
PF-06250112 is a potent, highly selective, orally bioavailable BTK inhibitor with an IC₅₀ of 0.5 nM, shows inhibitory effect toward *BMX nonreceptor* tyrosine kinase and TEC with IC₅₀**s of 0.9 nM and 1.2 nM, respectively .

HY-171294

Protein kinase inhibitor 16	Ser/Thr Kinase	Inflammation/Immunology Cancer
Protein kinase inhibitor 16 exhibits inhibitory activity against a variety of Ser/Thr kinase or receptor or non-receptor tyrosine kinase .

HY-171276

Anti-neuroinflammation agent 3	Ser/Thr Kinase	Inflammation/Immunology
Anti-neuroinflammation agent 3 (Compound A.10.3) exhibits inhibitory activity against a variety of Ser/Thr kinase or receptor or non-receptor tyrosine kinase .

HY-171293

Protein kinase inhibitor 15	Ser/Thr Kinase	Inflammation/Immunology Cancer
Protein kinase inhibitor 15 (Compound A.35.3) exhibits inhibitory activity against a variety of Ser/Thr kinase or receptor or non-receptor tyrosine kinase .

HY-E70725

FRK Recombinant Human Active Protein Kinase	Src	Cancer
FRK Recombinant Human Active Protein Kinase, a non-receptor tyrosine kinase Fyn-related kinase, is a member of the BRK family kinases (BFKs). FRK may be involved in tumor progression .

HY-130631

SHP2-IN-5	SHP2	Cancer
SHP2-IN-5 (compound 1) is an inhibitor of SHP2 (IC₅₀: 97 nM). SHP2 is a non-receptor protein tyrosine phosphatase associated with cell growth and proliferation. SHP2-IN-5 has the potential to inhibit cancer and SHP2-related human diseases .

HY-E70834

JAK1(JH1) Recombinant Human Active Protein Kinase	JAK	Cancer
JAK1 is a non-receptor tyrosine kinase that plays a critical role in cell signaling via type I/II cytokines and interferons (IFNs). JAK1(JH1) is a kinase domain. JAK1(JH1) Recombinant Human Active Protein Kinase is a recombinant JAK1(JH1) protein that can be used to study JAK1(JH1)-related functions .

HY-E70872

TYK2(JH1) Recombinant Human Active Protein Kinase	JAK	Cancer
TYK2 is a member of the JAK family of non-receptor tyrosine kinases that act together with signal transducer and activator of transcription (STAT) factors in mediating intracellular signal transduction. JAKs are characterized by dual kinase domain: a tyrosine kinase domain (JH1) that is preceded by a pseudokinase domain (JH2). TYK2(JH1) Recombinant Human Active Protein Kinase is a recombinant TYK2(JH1) protein that can be used to study TYK2(JH1)-related functions .

HY-E70874

TYK2(JH2) Recombinant Human Active Protein Kinase	JAK	Cancer
TYK2 is a member of the JAK family of non-receptor tyrosine kinases that act together with signal transducer and activator of transcription (STAT) factors in mediating intracellular signal transduction. JAKs are characterized by dual kinase domain: a tyrosine kinase domain (JH1) that is preceded by a pseudokinase domain (JH2). TYK2(JH2) Recombinant Human Active Protein Kinase is a recombinant TYK2(JH2) protein that can be used to study TYK2(JH2)-related functions .

HY-117900A

(Rac)-PF-06250112	Btk	Inflammation/Immunology
(Rac)-PF-0625011 is a racemate of PF-06250112. PF-06250112 is a potent, highly selective, orally bioavailable BTK inhibitor and shows inhibitory effect toward BMX nonreceptor tyrosine kinase and TEC .

HY-15376

Besipirdine HP 749 free base	Adrenergic Receptor	Neurological Disease
Besipirdine is a non-receptor-dependent cholinomimetic agent with noradrenergic activity. Besipirdine inhibits voltage-dependent sodium and potassium channels.

HY-171291

Protein kinase inhibitor 14	Ser/Thr Kinase	Inflammation/Immunology Cancer
Protein kinase inhibitor 14 (Compound 13) exhibits inhibitory effects against a variety of serine/threonine kinase and receptor/non-receptor tyrosine kinase .

HY-180326

NAT6-297775	Phosphatase SHP2	Cancer
NAT6-297775 (Compound 29) is a protein tyrosine phosphatase (PTP) inhibitor targeting non-receptor PTP SHP-2 with an IC₅₀ of 2.5 μM. NAT6-297775 can inhibit the RAS/MAP kinase signaling pathway. NAT6-297775 can be used for the research of cancer, such as leukemia .

HY-E70716

FAK aa411-686 Recombinant Human Active Protein Kinase	FAK	Cancer
Focal adhesion kinase (FAK), a non-receptor tyrosine kinase in the cytoplasm, couples with integrins and growth factor receptors to regulate cell adhesion, proliferation, migration, invasion, and metastasis. FAK is overexpressed and aberrantly activated in many cancer types, including triple negative breast cancer (TNBC). FAK aa411-686 Recombinant Human Active Protein Kinase is a recombinant FAK aa411-686 protein that can be used to study FAK aa411-686-related functions .

Cat. No.	Product Name

HY-L016

Protein Tyrosine Kinase Compound Library	1,578 compounds
Protein tyrosine kinases (PTKs) are key signaling molecules and important drug targets. Two classes of PTKs are present in cells: the transmembrane receptor PTKs (RTKs) and the nonreceptor PTKs. The RTK family includes the receptors for insulin and for many growth factors, such as EGFR, FGFR, PDGFR, VEGFR, and NGFR. RTKs are transmembrane glycoproteins that are activated by the binding of their ligands, and they transduce the extracellular signal to the cytoplasm by phosphorylating tyrosine residues on the receptors themselves (autophosphorylation) and on downstream signaling proteins. Their principal functions of PTKs involve the regulation of multicellular aspects of the organism. Cell to cell signals concerning growth, differentiation, adhesion, motility, and death are frequently transmitted through tyrosine kinases. In humans, tyrosine kinases have been demonstrated to play significant roles in the development of many disease states, including diabetes and cancers. MCE designs a unique collection of 1,578 compounds that act as a useful tool for PTKs-related drug screening and disease research.

Protein Tyrosine Kinase Compound Library

1,578 compounds

Protein tyrosine kinases (PTKs) are key signaling molecules and important drug targets. Two classes of PTKs are present in cells: the transmembrane receptor PTKs (RTKs) and the nonreceptor PTKs. The RTK family includes the receptors for insulin and for many growth factors, such as EGFR, FGFR, PDGFR, VEGFR, and NGFR. RTKs are transmembrane glycoproteins that are activated by the binding of their ligands, and they transduce the extracellular signal to the cytoplasm by phosphorylating tyrosine residues on the receptors themselves (autophosphorylation) and on downstream signaling proteins. Their principal functions of PTKs involve the regulation of multicellular aspects of the organism. Cell to cell signals concerning growth, differentiation, adhesion, motility, and death are frequently transmitted through tyrosine kinases. In humans, tyrosine kinases have been demonstrated to play significant roles in the development of many disease states, including diabetes and cancers.

MCE designs a unique collection of 1,578 compounds that act as a useful tool for PTKs-related drug screening and disease research.

Cat. No.	Product Name	Target	Research Area	Image

HY-P99025

Lebrikizumab 1 Publications Verification TNX-650; MILR1444A; RG3637	Interleukin Related	Neurological Disease Inflammation/Immunology
Lebrikizumab (TNX-650) is an IgG4 humanized anti-interleukin-13 (IL-13) mAb with anti-itch effects that specifically binds to IL-13 in a non-receptor binding domain and inhibits its function. Lebrikizumab inhibits the IL-13 driven Th2 inflammatory response and blocks the signaling of IL-4Rα/IL-13Rα1. Lebrikizumab can be used for the research of asthma, atopic dermatitis and neuroinflammatory diseases .

Species:	Human (24) Mouse (3)
Tag:	His (19) Tag Free (4) Avi (5) GST (8) Fc (1) Flag (1)
Source:	HEK293 (4) sf9 insect cells (5) Sf9 insect cells (14) E. coli (4)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P706110

	TYK2 Protein, Human (Active, sf9, His-GST) non-receptor tyrosine-protein kinase TYK2	Human	Sf9 insect cells

HY-P76669

	TCPTP Protein, Mouse (sf9, His) Tyrosine-protein phosphatase non-receptor type 2; MPTP; PTPN2	Mouse	Sf9 insect cells
	TCPTP is a non-receptor tyrosine-specific phosphatase that regulates multiple signaling pathways by dephosphorylating proteins such as INSR, EGFR, CSF1R, PDGFR, JAK, Src kinase and STAT.TCPTP acts in the nucleus and cytoplasm to regulate hematopoiesis, inflammation, cell proliferation, differentiation, and glucose homeostasis.TCPTP Protein, Mouse (sf9, His) is the recombinant mouse-derived TCPTP protein, expressed by Sf9 insect cells , with N-His labeled tag.

HY-P76103A

	TCPTP Protein, Human (sf9) Tyrosine-protein phosphatase non-receptor type 2; TCPTP; PTPN2; PTPT	Human	Sf9 insect cells
	TCPTP is a non-receptor tyrosine-specific phosphatase that critically regulates various kinases (INSR, EGFR, JAK, Src) affecting hematopoiesis, inflammation, cell proliferation, and glucose homeostasis. In the immune system, TCPTP regulates T cell receptor signaling and inhibits cytokine pathways (IL2, interferon). TCPTP Protein, Human (sf9) is the recombinant human-derived TCPTP protein, expressed by Sf9 insect cells , with tag free.

HY-P76103

	TCPTP Protein, Human (sf9, solution) Tyrosine-protein phosphatase non-receptor type 2; TCPTP; PTPN2; PTPT	Human	Sf9 insect cells
	TCPTP is a non-receptor tyrosine-specific phosphatase that critically regulates various kinases (INSR, EGFR, JAK, Src) affecting hematopoiesis, inflammation, cell proliferation, and glucose homeostasis. In the immune system, TCPTP regulates T cell receptor signaling and inhibits cytokine pathways (IL2, interferon). TCPTP Protein, Human (sf9, solution) is the recombinant human-derived TCPTP protein, expressed by Sf9 insect cells, with tag free.

HY-P76557

	PTPN12 Protein, Human (sf9) Tyrosine-protein phosphatase non-receptor type 12; PTP-PEST; PTPG1	Human	Sf9 insect cells
	The PTPN12 protein is a multifunctional enzyme that can dephosphorylate a variety of proteins and regulate cell signaling cascades. According to literature, PTPN12 selectively targets tyrosine kinases such as ERBB2 and PTK2B/PYK2 to control related pathways. PTPN12 Protein, Human (sf9) is the recombinant human-derived PTPN12 protein, expressed by Sf9 insect cells, with tag free.

HY-P73685

	PTP1B Protein, Human (His) 1 Publications Verification PTP-1B; PTPN1; Tyrosine-protein phosphatase non-receptor type 1	Human	E. coli
	PTP1B is an important tyrosine protein phosphatase that regulates the endoplasmic reticulum unfolded protein response by dephosphorylating EIF2AK3/PERK and inhibiting its kinase activity. It affects the signaling cascade induced by CKII and p60c-src, and may regulate the EFNA5-EPHA3 pathway, affecting cell reorganization. PTP1B Protein, Human (His) is the recombinant human-derived PTP1B protein, expressed by E. coli , with N-His labeled tag.

HY-P76104

	TCPTP Protein, Human (sf9, His-GST) Tyrosine-protein phosphatase non-receptor type 2; TCPTP; PTPN2; PTPT	Human	Sf9 insect cells
	TCPTP is a non-receptor tyrosine-specific phosphatase that critically regulates various kinases (INSR, EGFR, JAK, Src) affecting hematopoiesis, inflammation, cell proliferation, and glucose homeostasis. In the immune system, TCPTP regulates T cell receptor signaling and inhibits cytokine pathways (IL2, interferon). TCPTP Protein, Human (sf9, His-GST) is the recombinant human-derived TCPTP protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.

HY-P76558

	PTPN12 Protein, Human (sf9, His-GST) Tyrosine-protein phosphatase non-receptor type 12; PTP-PEST; PTPG1	Human	Sf9 insect cells
	The PTPN12 protein is a multifunctional enzyme that can dephosphorylate a variety of proteins and regulate cell signaling cascades. According to literature, PTPN12 selectively targets tyrosine kinases such as ERBB2 and PTK2B/PYK2 to control related pathways. PTPN12 Protein, Human (sf9, His-GST) is the recombinant human-derived PTPN12 protein, expressed by Sf9 insect cells , with N-GST, N-His labeled tag.

HY-P74549

	SHP-2 Protein, Mouse (HEK293, His) Tyrosine-protein phosphatase non-receptor type 11; SH-PTP2; SHP-2; Ptpn11	Mouse	HEK293
	SHP-2 Protein functions downstream of diverse receptor and cytoplasmic tyrosine kinases, participating in signal transduction from the cell surface to the nucleus.It positively regulates the MAPK pathway and dephosphorylates key proteins like GAB1, ARHGAP35, EGFR, ROCK2, CDC73, and SOX9.Additionally, SHP-2 dephosphorylates NEDD9/CAS-L to modulate cellular processes.SHP-2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived SHP-2 protein, expressed by HEK293 , with C-His labeled tag.

HY-P704172

	TYK2 Protein, Human (Active, sf9, His) TYK2; tyrosine kinase 2; non-receptor tyrosine-protein kinase TYK2; JTK1	Human	Sf9 insect cells
	TYK2 Protein, Human (Active, sf9, His) is the recombinant human-derived TYK2 protein, expressed by Sf9 insect cells, with N-His tag.

HY-P704967

	TYK2 Protein, Human (Inactive, sf9, His) TYK2; tyrosine kinase 2; non-receptor tyrosine-protein kinase TYK2; JTK1	Human	sf9 insect cells

HY-P705947

	TYK2 Protein, Human (Active, sf9, GST) TYK2; tyrosine kinase 2; non-receptor tyrosine-protein kinase TYK2; JTK1	Human	Sf9 insect cells
	TYK2 Protein, Human (Active, sf9, GST) is the recombinant human-derived TYK2 protein, expressed by Sf9 insect cells, with N-His tag.

HY-P75542

	ACK1 Protein, Human (Active, sf9, GST) Activated CDC42 kinase 1; Tyrosine kinase non-receptor protein 2; TNK2	Human	Sf9 insect cells
	The ACK1 protein is a non-receptor tyrosine protein and serine/threonine protein kinase that orchestrates cellular physiology by affecting cell spreading, migration, survival, growth, and proliferation. It phosphorylates AKT1, AR, MCF2, WASL and WWOX, affecting various cellular processes. ACK1 Protein, Human (sf9, GST) is the recombinant human-derived ACK1 protein, expressed by Sf9 insect cells , with N-GST labeled tag.

HY-P77170

	PTP-MEG2/PTPN9 Protein, Human (sf9, His-GST) Tyrosine-protein phosphatase non-receptor type 9; PTPase MEG2; PTPN9	Human	Sf9 insect cells
	The PTP-MEG2/PTPN9 protein is a multifunctional protein tyrosine phosphatase with potential roles related to hydrophobic ligand transfer or Golgi function. It operates in a complex cellular environment, demonstrating the versatility of different molecular processes. PTP-MEG2/PTPN9 Protein, Human (sf9, His-GST) is the recombinant human-derived PTP-MEG2/PTPN9 protein, expressed by Sf9 insect cells , with C-His, N-GST labeled tag.

HY-P705809

	TYK2 Protein, Human (Inactive, sf9, His-Avi) TYK2; tyrosine kinase 2; non-receptor tyrosine-protein kinase TYK2; JTK1	Human	sf9 insect cells

HY-P705810

	TYK2 Protein, Human (Inactive, Biotinylated, sf9, His-Avi) TYK2; tyrosine kinase 2; non-receptor tyrosine-protein kinase TYK2; JTK1	Human	sf9 insect cells

HY-P73649

	SHP-1 Protein, Mouse (sf9, His-GST) Tyrosine-protein phosphatase non-receptor type 6; 70Z-SHP; PTP-1C; SHP-1; Ptpn6	Mouse	Sf9 insect cells
	SHP-1 Protein modulates signaling from tyrosine-phosphorylated cell surface receptors, including KIT and EGFR. It enhances the inhibition of mast cell activation via the Lilrb4a receptor. The SH2 regions interact with cellular components to regulate its phosphatase activity. In collaboration with MTUS1, it induces UBE2V2 expression upon angiotensin II stimulation. SHP-1 plays a crucial role in hematopoiesis. SHP-1 Protein, Mouse (sf9, His-GST) is the recombinant mouse-derived SHP-1 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.

HY-P702722

	TYK2 Protein, Human (Active, Biotinylated, sf9, His, Flag, Avi) TYK2; tyrosine kinase 2; non-receptor tyrosine-protein kinase TYK2; JTK1	Human	Sf9 insect cells
	TYK2 Protein, Human (Biotinylated, sf9, His, Flag, Avi) is the recombinant human-derived TYK2, expressed by Sf9 insect cells , with His, Avi, Flag labeled tag. ,

HY-P704877

	SHP-2 Protein, Human (N-His) protein tyrosine phosphatase, non-receptor type 11; Noonan syndrome 1 , NS1; tyrosine-protein phosphatase non-receptor type 11; BPTP3; PTP2C; SH PTP2; SHP 2; SHP2; PTP-2C; protein tyrosine phosphatase-2; protein-tyrosine phosphatase 1D; protein-tyrosine phosphatase 2C; CFC; NS1; PTP-1D; SH-PTP2; SH-PTP3; MGC14433;	Human	E. coli

HY-P700618

	SHP-2 Protein, Human (T253M, Q257L, His) 1 Publications Verification protein tyrosine phosphatase, non-receptor type 11; Noonan syndrome 1 , NS1; tyrosine-protein phosphatase non-receptor type 11; BPTP3; PTP2C; SH PTP2; SHP 2; SHP2; PTP-2C; protein tyrosine phosphatase-2; protein-tyrosine phosphatase 1D; protein-tyrosine phosphatase 2C; CFC; NS1; PTP-1D; SH-PTP2; SH-PTP3; MGC14433;	Human	E. coli
	The SHP-2 protein is a key player downstream of the receptor and cytoplasmic protein tyrosine kinases, facilitating signal transduction from the cell surface to the nucleus. It actively regulates the MAPK pathway and dephosphorylates key substrates, including GAB1, ARHGAP35, EGFR, ROCK2 ("Tyr-722"), and CDC73. SHP-2 Protein, Human (T253M, Q257L, His) is the recombinant human-derived SHP-2 protein, expressed by E. coli , with N-6*His labeled tag and T253M, Q257L mutation.

HY-P71141

	SHP-1 Protein, Human (His) 1 Publications Verification Tyrosine-Protein Phosphatase non-receptor Type 6; Hematopoietic Cell Protein-Tyrosine Phosphatase; Protein-Tyrosine Phosphatase 1C; PTP-1C; Protein-Tyrosine Phosphatase SHP-1; SH-PTP1; PTPN6; HCP; PTP1C	Human	E. coli
	SHP-1 Protein modulates signaling from tyrosine-phosphorylated cell surface receptors, including KIT and EGFR. It enhances the inhibition of mast cell activation via the Lilrb4a receptor. The SH2 regions interact with cellular components to regulate its phosphatase activity. In collaboration with MTUS1, it induces UBE2V2 expression upon angiotensin II stimulation. SHP-1 plays a crucial role in hematopoiesis. SHP-1 Protein, Human (His) is the recombinant human-derived SHP-1 protein, expressed by E. coli , with C-6*His labeled tag.

HY-P70484

	SIRP alpha/CD172a Protein, Human (CAA71403, HEK293, His) Tyrosine-Protein Phosphatase non-receptor Type Substrate 1; SHP Substrate 1; SHPS-1; Brain Ig-Like Molecule with Tyrosine-Based Activation Motifs; Bit; CD172 Antigen-Like Family Member A; Inhibitory Feceptor SHPS-1; Macrophage Fusion receptor; MyD-1 Antigen; Signa	Human	HEK293
	SIRP alpha/CD172a Protein, Human (CAA71403.1, HEK 293, His) , as a recombinant protein produced in HEK293 cells, is a polypeptide chain with a His tag.

HY-P703856

	SIRP alpha V5/CD172a Protein, Human (HEK293, His, Avi) Tyrosine-protein phosphatase non-receptor type substrate 1; SHP substrate 1; SHPS-1; Brain Ig-like molecule with tyrosine-based activation motifs (Bit); CD172 antigen-like family member A; Inhibitory receptor SHPS-1; Macrophage fusion receptor; MyD-1 antigen; CD172a	Human	HEK293
	The SIRP α V4/CD172a protein is an immunoglobulin-like cell surface receptor for CD47 that acts as a docking protein to facilitate the translocation of PTPN6, PTPN11, and other partners to the plasma membrane. It supports the adhesion of cerebellar neurons, promotes neurite growth, and promotes glial cell attachment. SIRP alpha V5/CD172a Protein, Human (HEK293, His, Avi) is the recombinant human-derived SIRP alpha V5/CD172a protein, expressed by HEK293, with C-His and C-Avi labeled tag.

HY-P704882

	SIRP alpha/CD172a Protein, Human (119a.a, HEK293, Llama Fc) Tyrosine-protein phosphatase non-receptor type substrate 1; SHP substrate 1; SHPS-1; Brain Ig-like molecule with tyrosine-based activation motifs (Bit); CD172 antigen-like family member A; Inhibitory receptor SHPS-1; Macrophage fusion receptor; MyD-1 antigen; CD172a	Human	HEK293

HY-P706088

	PTK2B Protein, Human (Active, 331a.a, sf9) Protein-tyrosine kinase 2-beta; Calcium-dependent tyrosine kinase; CADTK; Calcium-regulated non-receptor proline-rich tyrosine kinase; Cell adhesion kinase beta; CAK-beta; CAKB; Focal adhesion kinase 2; FADK 2; Proline-rich tyrosine kinase 2; Related adhesion focal tyrosine kinase; RAFTK; FAK2; PYK2; RAFTK	Human	Sf9 insect cells

HY-P705867

	PTK2B Protein, Human (Active, Biotinylated, sf9, Avi) PTK2B; PTK2B protein tyrosine kinase 2 beta; FAK2, protein tyrosine kinase 2 beta; protein-tyrosine kinase 2-beta; CADTK; CAKB; PTK; PYK2; RAFTK; FADK 2; CAK-beta; protein kinase B; focal adhesion kinase 2; cell adhesion kinase beta; proline-rich tyrosine kinase 2; calcium-dependent tyrosine kinase; related adhesion focal tyrosine kinase; calcium-regulated non-receptor proline-rich tyrosine kinase; PKB; FAK2; FADK2	Human	sf9 insect cells

HY-P705866

	PTK2B Protein, Human (277a.a, sf9) PTK2B; PTK2B protein tyrosine kinase 2 beta; FAK2, protein tyrosine kinase 2 beta; protein-tyrosine kinase 2-beta; CADTK; CAKB; PTK; PYK2; RAFTK; FADK 2; CAK-beta; protein kinase B; focal adhesion kinase 2; cell adhesion kinase beta; proline-rich tyrosine kinase 2; calcium-dependent tyrosine kinase; related adhesion focal tyrosine kinase; calcium-regulated non-receptor proline-rich tyrosine kinase; PKB; FAK2; FADK2	Human	sf9 insect cells

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Host:	Mouse (6) Rabbit (16)
Reactivity:	Human (22) Rat (5) Mouse (6) Rabbit (1) Dog (1) Pig (1)
Application:	IHC-P (16) ICC/IF (10) IF-Tissue (1) IP (6) IHC-F (3) WB (22) FC (7) ELISA (3)
Isotype:	IgG (16) IgG1 (1) IgG2a (3)
Conjugation:	Non-conjugated (22) Biotin (3)
Clonality:	Monoclonal (16) Recombinant (9)
Modification:	Phosphorylated (2) Unmodified (15)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P85402

	Tyk 2 Antibody (YA5094) TYK2; non-receptor tyrosine-protein kinase TYK2	WB, IHC-P	Human
	Tyk 2 Antibody (YA5094) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to Tyk 2.

HY-P85392

	TNK1 Antibody (YA5084) TNK1; non-receptor tyrosine-protein kinase TNK1; CD38 negative kinase 1	WB, ELISA	Human
	TNK1 Antibody (YA5084) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to TNK1.

HY-P82031

	PTP1B Antibody (YA1776) PTPN1; PTP1B; Tyrosine-protein phosphatase non-receptor type 1; Protein-tyrosine phosphatase 1B; PTP-1B	WB, IHC-F, IHC-P, ICC/IF	Human
	PTP1B Antibody (YA1776) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PTP1B.

HY-P82031A

	PTP1B Antibody (YA1776)(PBS only) PTPN1; PTP1B; Tyrosine-protein phosphatase non-receptor type 1; Protein-tyrosine phosphatase 1B; PTP-1B	WB, IHC-F, IHC-P, ICC/IF	Human
	PTP1B Antibody (YA1776) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PTP1B.

HY-P81300A

	Phospho-PTP1B (Ser378) Antibody (YA1028) PTPN1; PTP1B; Tyrosine-protein phosphatase non-receptor type 1; Protein-tyrosine phosphatase 1B; PTP-1B	WB, IHC-P	Human
	Phospho-PTP1B (Ser378) Antibody (YA1028) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-PTP1B (Ser378).

HY-P81300

	Phospho-PTP1B (Ser352) Antibody (YA1027) PTPN1; PTP1B; Tyrosine-protein phosphatase non-receptor type 1; Protein-tyrosine phosphatase 1B; PTP-1B	WB, ICC/IF, IP	Human
	Phospho-PTP1B (Ser352) Antibody (YA1027) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-PTP1B (Ser352).

HY-P81300AA

	Phospho-PTP1B (Ser378) Antibody (YA1028)(PBS only) PTPN1; PTP1B; Tyrosine-protein phosphatase non-receptor type 1; Protein-tyrosine phosphatase 1B; PTP-1B	WB, IHC-P	Human
	Phospho-PTP1B (Ser378) Antibody (YA1028) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-PTP1B (Ser378).

HY-P81307A

	SHP1 Antibody (YA1045) PTPN6; HCP; PTP1C; Tyrosine-protein phosphatase non-receptor type 6; Hematopoietic cell protein-tyrosine phosphatase; Protein-tyrosine phosphatase 1C; PTP-1C; Protein-tyrosine phosphatase SHP-1; SH-PTP1	WB, IHC-P, ICC/IF, FC	Human
	SHP1 Antibody (YA1045) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SHP1.

HY-P81307

	SHP1 Antibody (YA1044) PTPN6; HCP; PTP1C; Tyrosine-protein phosphatase non-receptor type 6; Hematopoietic cell protein-tyrosine phosphatase; Protein-tyrosine phosphatase 1C; PTP-1C; Protein-tyrosine phosphatase SHP-1; SH-PTP1	WB, IP	Human
	SHP1 Antibody (YA1044) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to SHP1.

HY-P81307AA

	SHP1 Antibody (YA1045)(PBS only) PTPN6; HCP; PTP1C; Tyrosine-protein phosphatase non-receptor type 6; Hematopoietic cell protein-tyrosine phosphatase; Protein-tyrosine phosphatase 1C; PTP-1C; Protein-tyrosine phosphatase SHP-1; SH-PTP1	WB, IHC-P, ICC/IF, FC	Human
	SHP1 Antibody (YA1045) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SHP1.

HY-P81898

	SHP2 Antibody (YA1643) PTPN11; PTP2C; SHPTP2; Tyrosine-protein phosphatase non-receptor type 11; Protein-tyrosine phosphatase 1D; PTP-1D; Protein-tyrosine phosphatase 2C; PTP-2C; SH-PTP2; SHP-2; Shp2; SH-PTP3	WB, IHC-P, IP	Human
	SHP2 Antibody (YA1643) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SHP2.

HY-P810492

	SIRP alpha Antibody (YA9785) SIRPA, BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP, Tyrosine-protein phosphatase non-receptor type substrate 1, SHP substrate 1, SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Bit, CD172 antigen-like family member A, Inhibito	WB, IHC-P, ICC/IF, FC	Human
	SIRP alpha Antibody (YA9785) is a Rabbit-derived and non-conjugated IgG Monoclonal antibody, targeting to SIRP alpha.

HY-P80877

	PYK2 Antibody (YA682) PTK2B; FAK2; PYK2; RAFTK; Protein-tyrosine kinase 2-beta; Calcium-dependent tyrosine kinase; CADTK; Calcium-regulated non-receptor proline-rich tyrosine kinase; Cell adhesion kinase beta; CAK-beta; CAKB; Focal adhesion kinase 2; FADK 2; Pro	WB, IHC-P	Human
	PYK2 Antibody (YA682) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to PYK2.

HY-P85341

	PYK2 Antibody (YA5033) PTK2B; FAK2; PYK2; RAFTK; Protein-tyrosine kinase 2-beta; Calcium-dependent tyrosine kinase; CADTK; Calcium-regulated non-receptor proline-rich tyrosine kinase; Cell adhesion kinase beta; CAK-beta; CAKB; Focal adhesion kinase 2; FADK 2; Pro	WB, IHC-P, ICC/IF, IF-Tissue, FC, IHC-F	Human, Mouse, Rat
	PYK2 Antibody (YA5033) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to PYK2.

HY-P85462

	PYK2 Antibody (YA5154) PTK2B; FAK2; PYK2; RAFTK; Protein-tyrosine kinase 2-beta; Calcium-dependent tyrosine kinase; CADTK; Calcium-regulated non-receptor proline-rich tyrosine kinase; Cell adhesion kinase beta; CAK-beta; CAKB; Focal adhesion kinase 2; FADK 2; Pro	WB	Human, Mouse, Dog, Pig, Rabbit
	PYK2 Antibody (YA5154) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to PYK2.

HY-P86140

	PYK2 Antibody (YA5832) PTK2B; FAK2; PYK2; RAFTK; Protein-tyrosine kinase 2-beta; Calcium-dependent tyrosine kinase; CADTK; Calcium-regulated non-receptor proline-rich tyrosine kinase; Cell adhesion kinase beta; CAK-beta; CAKB; Focal adhesion kinase 2; FADK 2; Pro	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	PYK2 Antibody (YA5832) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PYK2.

HY-P86320

	SH-PTP2 Antibody (YA6012) PTPN11; PTP2C; SHPTP2; Tyrosine-protein phosphatase non-receptor type 11; Protein-tyrosine phosphatase 1D; PTP-1D; Protein-tyrosine phosphatase 2C; PTP-2C; SH-PTP2; SHP-2; Shp2; SH-PTP3	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	SH-PTP2 Antibody (YA6012) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SH-PTP2.

HY-P81898A

	SHP2 Antibody (YA1643)(PBS only) PTPN11; PTP2C; SHPTP2; Tyrosine-protein phosphatase non-receptor type 11; Protein-tyrosine phosphatase 1D; PTP-1D; Protein-tyrosine phosphatase 2C; PTP-2C; SH-PTP2; SHP-2; Shp2; SH-PTP3	WB, IHC-P, IP	Human
	SHP2 Antibody (YA1643) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SHP2.

HY-P81616

	SIRP alpha Antibody (YA1361) SIRPA; BIT; MFR; MYD1; PTPNS1; SHPS1; SIRP; Tyrosine-protein phosphatase non-receptor type substrate 1; SHP substrate 1; SHPS-1; Brain Ig-like molecule with tyrosine-based activation motifs; Bit; CD172 antigen-like family member A; Inhibito	WB, FC	Human, Mouse, Rat
	SIRP alpha Antibody (YA1361) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SIRP alpha.

HY-P80877A

	PYK2 Antibody (YA682)(PBS only) PTK2B; FAK2; PYK2; RAFTK; Protein-tyrosine kinase 2-beta; Calcium-dependent tyrosine kinase; CADTK; Calcium-regulated non-receptor proline-rich tyrosine kinase; Cell adhesion kinase beta; CAK-beta; CAKB; Focal adhesion kinase 2; FADK 2; Pro	WB, IHC-P	Human
	PYK2 Antibody (YA682) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to PYK2.

HY-P87102

	TCPTP Antibody (YA6795) Protein tyrosine phosphatase non receptor type 2 antibody; PTN2 antibody; PTN2_HUMAN antibody; PTPN 2 antibody; Ptpn2 antibody; PTPT antibody; T cell protein tyrosine phosphatase antibody; T-cell protein-tyrosine phosphatase antibody; TC PTP antibody; TCELLPTP antibody; Protein tyrosine phosphatase non receptor type 2 antibody; PTN2 antibody; PTN2_HUMAN antibody; PTPN 2 antibody; Ptpn2 antibody; PTPT antibody; T cell protein tyrosine phosphatase antibody; T-cell protein-tyrosine phosphatase antibody; TC PTP antibody; TCELLPTP antibody; TCPTP antibody; Tyrosine protein phosphatase non receptor type 2 antibody; Tyrosine-protein phosphatase non-receptor type 2 antibody;	WB, FC	Human, Mouse, Rat
	TCPTP Antibody (YA6795) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TCPTP.

HY-P87315

	PTPN14 Antibody (YA6998) Cytoskeletal associated protein tyrosine phosphatase antibody; MGC126803 antibody; PEZ antibody; Phosphatase with ezrin domain antibody; Protein tyrosine phosphatase non receptor type 14 antibody; Protein tyrosine phosphatase pez antibody; Protein-tyrosine phosphatase pez antibody; PTN14_HUMAN antibody; PTP 36 antibody; PTP36 antibody	WB, ICC/IF, IHC-P, FC	Human
	PTPN14 Antibody (YA6998) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PTPN14.

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