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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
nonimmunosuppressive
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "nonimmunosuppressive" in MCE Product Catalog:
2
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Research Areas:
GPI-1485 (GM1485), a nonimmunosuppressive immunophilin ligand, promotes neurofunctional improvement and neural regeneration following stroke .
Cat. No.: HY-106345
CAS No.: 892494-07-4
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ILS-920 is a nonimmunosuppressive Rapamycin analog with reduced immunosuppressive activity and potent neuroprotective activity. ILS-920 binds selectively to the immunophilin FKBP52 and to the β1-subunit of L-type voltage-gated calcium channels (VGCC). ILS-920 shows 200-fold selectivity for FKBP52 versus FKBP12 .
Cat. No.: HY-117720
CAS No.: 1351056-65-9
OSU-2S is a potent PKCδ activator. OSU-2S inhibits cell proliferation and migration. OSU-2S decreases the expression of p-ERK1/2, increases the expression of PKCδ (38 kDa) when combined with Sorafenib (HY-10201). OSU-2S induces Apoptosis. OSU-2S slao is a non-immunosuppressive analogue of FTY720. OSU-2S shows anticancer activity .
Cat. No.: HY-P3351
CAS No.: 935735-70-9
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Cat. No.: HY-128924
CAS No.: 1589093-01-5
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NIM258 is a potent nonimmunosuppressive cyclophilin inhibitor (cyclophilin A Kd = 1.2 nM) with anti-HCV activity (EC50 = 40 nM). NIM258 can be used for HCV infection research .
Cat. No.: HY-P1360
CAS No.: 1038781-13-3
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Cat. No.: HY-179354
CAS No.: 292606-90-7
AP21998 is a non-immunosuppressive derivative of Rapamycin (HY-10219) and an inducer of exocytosis. By binding to mutant FKBP (F36M), AP21998 dissociates fusion protein aggregates in the endoplasmic reticulum into monomers, which then enter the Golgi apparatus to be cleaved by furin protease, ultimately releasing the polypeptide. AP21998 can be used in cancer research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
