3 Results for "

paralytic shellfish poisoning

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "paralytic shellfish poisoning" in MCE Product Catalog:

Cat. No.: HY-135000
CAS No.: 58911-04-9
Synonyms: DcSTX; DecarbamoylSTX
Decarbamoylsaxitoxin is a sodium channel inhibitor that blocks the influx of sodium ions through the membranes of excitable nerves and skeletal muscle cells, thereby preventing the formation of action potentials. Decarbamoylsaxitoxin is an acidic hydrolysis product of saxitoxin, and its toxic effects on mice are identical to those of saxitoxin. Decarbamoylsaxitoxin inhibits veratridine- and ouabain-induced swelling and lysis of mouse neuroblastoma cells by blocking Na + channels. Decarbamoylsaxitoxin can be used in studies related to paralytic shellfish poisoning .
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Cat. No.: HY-19605
CAS No.: 60508-89-6
Target:  

Sodium Channel

Research Areas:  

Neurological Disease Cancer

Gonyautoxin II is a paralytic shellfish poisoning toxin. Gonyautoxin II can block of the voltage-gated sodium channels at axonal level, impeding nerve impulse propagation. Gonyautoxin II has killing activity against mouse neuroblastoma cells. Gonyautoxin II can be used for the researches of cancer and neurological disease .
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Cat. No.: HY-W343059
CAS No.: 60537-65-7
Synonyms: GTX-III
Target:  

Sodium Channel

Research Areas:  

Neurological Disease Cancer

Gonyautoxin III (GTX-III) is a paralytic shellfish poisoning toxin. Gonyautoxin III can block of the voltage-gated sodium channels at axonal level with an IC50 of 14.9 nM, impeding nerve impulse propagation. Gonyautoxin III has killing activity against mouse neuroblastoma cells. Gonyautoxin III can be used for the researches of cancer and neurological disease .
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