Gonyautoxin II
Gonyautoxin II is a paralytic shellfish poisoning toxin. Gonyautoxin II can block of the voltage-gated sodium channels at axonal level, impeding nerve impulse propagation. Gonyautoxin II has killing activity against mouse neuroblastoma cells. Gonyautoxin II can be used for the researches of cancer and neurological disease.
For research use only. We do not sell to patients.
- CAS No.: 60508-89-6
- Formula: C10H17N7O8S
- Molecular Weight:395.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 60508-89-6
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Molecular Weight 395.35
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Formula C10H17N7O8S
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SMILES
OC1([C@]23[C@](N=C(N3)N)([H])[C@@H](N=C(N2C[C@H]1OS(=O)(O)=O)N)COC(N)=O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Jellett JF, et al. Toxicological evaluation of saxitoxin, neosaxitoxin, gonyautoxin II, gonyautoxin II plus III and decarbamoylsaxitoxin with the mouse neuroblastoma cell bioassay. Toxicol In Vitro. 1995 Feb;9(1):57-65. [Content Brief]
[2]. Walker JR, et al. Divergent Synthesis of Natural Derivatives of (+)-Saxitoxin Including 11-Saxitoxinethanoic Acid. Angew Chem Int Ed Engl. 2019 Feb 4;58(6):1689-1693. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Gonyautoxin II Related Classifications
HY-19605 Related Classifications
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