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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
pentamers
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "pentamers" in MCE Product Catalog:
Cat. No.: HY-164279
CAS No.: 1207615-74-4
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YTR107 is a radiation sensitizer. YTR107 binds to nucleophosmin1 (NPM1) and inhibits pentamer formation. YTR107 inhibits recruitment of nucleophosmin to sites of DNA damage, suppresses repair of DNA double strand breaks, and enhances radiosensitization .
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Aβ42 agonist-2 (compound 7b) is a small molecule compound that can promote Aβ42 aggregation. Aβ42 agonist-2 can interact with Aβ42 oligomers and pentamers to promote nontoxic aggregate self-assembly and rapid fibril formation. Aβ42 agonist-2 prevents Aβ42-induced cytotoxicity in HT22 hippocampal neuronal cells .
Cat. No.: HY-148548
CAS No.: 1175142-38-7
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p-HTAA is a pentamer hydrogen thiophene acetic acid. p-HTAA specifically labels Aβ deposits in the mice living brain .
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Aβ42 agonist-1 is a compound that can promote Aβ42 aggregation. Aβ42 agonist-1 can interact with Aβ42 oligomers and pentamers to promote nontoxic aggregate self-assembly and rapid fibril formation. Aβ42 agonist-1 prevents Aβ42-induced cytotoxicity in HT22 hippocampal neuronal cells .
Cat. No.: HY-W749229
Cat. No.: HY-P12139
CAS No.: 117138-20-2
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GLFGAIAGFIENGWEGMIDG is an influenza hemagglutinin fusion peptide and membrane disruptor composed of 20 amino acids. GLFGAIAGFIENGWEGMIDG transiently adopts an activated double-helix conformation under low pH conditions; meanwhile, it self-assembles into oligomers with a stable trimeric core, which further form pentamers and hexamers capable of inducing membrane bending, thinning and long-range disruption. GLFGAIAGFIENGWEGMIDG promotes the protrusion of lipid tails and the penetration of polar heads in phospholipid membranes, and is widely used in influenza-related studies .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
