2 Results for "

pharmacogenetics

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "pharmacogenetics" in MCE Product Catalog:

Cat. No.: HY-107121
CAS No.: 676501-25-0
Synonyms: LY 2196044
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

Ondelopran (LY 2196044) is a non-selective opioid receptor antagonist. Ondelopran inhibits the release of dopamine in the nucleus accumbens induced by alcohol, reduces the rewarding effect of alcohol consumption, and lowers the craving. Ondelopran can be used for alcohol use disorder (AUD) .
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Cat. No.: HY-E72100
Target:  

Cytochrome P450

Research Areas:  

Others

Human CYP2D6, Reductase+b5 refers to a near-physiological recombinant microsomal system co-expressed in insect cells, consisting of human cytochrome P450 2D6, NADPH-P450 oxidoreductase (CPR) and cytochrome b5. Human CYP2D6 is a human cytochrome P450 subtype belonging to the CYP2 family, and also serves as a major metabolic enzyme capable of crossing the blood-brain barrier. Its expression is centered in the human liver (also detected in the brain) and exhibits high polymorphism .
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