20 Results for "

skin-permeable

" in MedChemExpress (MCE) Product Catalog:
Products (20)

20 Results for "skin-permeable" in MCE Product Catalog:

49
49 Publications Verification
Cat. No.: HY-B0568
CAS No.: 30652-11-0
Deferiprone is a potent, orally active, brain-penetrant, cell-penetrant, skin-permeable, free iron chelating agent. Deferiprone inhibits the proliferation and migration, and stimulates apoptosis in tumor cell. Deferiprone can inhibit KDM. Deferiprone has antianemic, neuroprotective, anti-inflammatory, antioxidant, and antidotal activity. Deferiprone can be used in cancer, cardiovascular disease, infection, inflammation, and neurological disease study .
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2
2 Cited Publications
Cat. No.: HY-P0033
CAS No.: 616204-22-9
Synonyms: Acetyl hexapeptide-3; Acetyl hexapeptide-8
Target:  

Calcium Channel

Research Areas:  

Neurological Disease

Argireline (Acetyl hexapeptide-3) is a non-toxic, skin-permeable, antiwrinkle peptide. Argireline significantly inhibits Ca 2+ dependent neurotransmitter release (acetylcholine) at the neuromuscular junction. Argireline has antiwrinkle and anti-aging activity .
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1
1 Cited Publications
Cat. No.: HY-W009326
CAS No.: 59227-89-3
Laurocapram is a chemical penetration enhancer that increases the permeability of compounds through the skin and mucous membranes, thereby improving their local or systemic efficacy. Laurocapram improves the skin permeability of a variety of hydrophilic and lipophilic compounds .
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Cat. No.: HY-W141881
CAS No.: 97-78-9
N-lauroylsarcosine is an anionic surfactant. N-lauroylsarcosine has antiviral activity against HSV-2 strain 333 and HSV-1 strain F. N-lauroylsarcosine synergistically increases skin permeability with 25-50% ethanol. N-lauroylsarcosine can be used to study HSV-2 infection .
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Cat. No.: HY-B0568R
CAS No.: 30652-11-0
Deferiprone (Standard) is the analytical standard of Deferiprone. This product is intended for research and analytical applications. Deferiprone is a potent, orally active, brain-penetrant, cell-penetrant, skin-permeable, free iron chelating agent. Deferiprone inhibits the proliferation and migration, and stimulates apoptosis in tumor cell. Deferiprone has antianemic, neuroprotective, anti-inflammatory, antioxidant, and antidotal activity. Deferiprone can be used in cancer, cardiovascular disease, infection, inflammation, and neurological disease study .
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Cat. No.: HY-141573
CAS No.: 143-28-2
Purity:  84.00%
Research Areas:  

Neurological Disease Cancer

Oleyl alcohol is an anti-tumor compound that inhibits tumor growth. Oleyl alcohol induces cytotoxicity, cell death and apoptosis. The intracellular accumulation of Oleyl alcohol correlates with its cytotoxicity against tumor cells. Oleyl alcohol forms enhancer-enriched fluid domains in stratum corneum lipids, increases the retention of diclofenac diethylamine in ex vivo human epidermis and dermis, and enhances the skin permeability of diclofenac diethylamine. Oleyl alcohol can be used in studies related to neuroblastoma .
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Cat. No.: HY-W250316
CAS No.: 37318-31-3
Synonyms: Sucrose Stearate, Type II, USP
Alpha-d-Glucopyranoside, beta-d-fructofuranosyl, octadecanoate (Sucrose Stearate, Type II, USP) is a non-ionic surfactant. Alpha-d-Glucopyranoside, beta-d-fructofuranosyl, octadecanoate enhances the skin permeability of formulations .
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Cat. No.: HY-P5107
CAS No.: 121052-30-0
Synonyms: LMWP; TDSP5
Target:  

VEGFR

Research Areas:  

Cancer

Low molecular weight protamine (LMWP;TDSP5) is a truncated arginine-rich protamine peptide, as well as a heparin/low-molecular-weight heparin antidote and a cell-penetrating delivery carrier. Low molecular weight protamine neutralizes heparin-induced anticoagulant activities, including aPTT, anti-Xa and anti-IIa activities, and also neutralizes anti-Xa activity of commercially available low-molecular-weight heparin preparations. Low molecular weight protamine translocates across mammalian cell membranes, delivers conjugated impermeable molecules across tumor tissues, enhances skin permeability of conjugated epidermal growth factor, and accelerates wound healing when conjugated with epidermal growth factor. Low molecular weight protamine retains the in vitro cell proliferation activity of conjugated EGF, and also enables site-specific conjugation with peptides or proteins via genetic recombination. Low molecular weight protamine can be used in studies related to colon adenocarcinoma, skin wounds and diabetic skin wounds .
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Cat. No.: HY-P0033A
CAS No.: 2484708-86-1
Synonyms: Acetyl hexapeptide-3 acetate; Acetyl hexapeptide-8 acetate
Target:  

Calcium Channel

Research Areas:  

Neurological Disease

Argireline acetate (Acetyl hexapeptide-3 acetate) is a non-toxic, skin-permeable, antiwrinkle peptide. Argireline acetate significantly inhibits Ca 2+ dependent neurotransmitter release (acetylcholine) at the neuromuscular junction. Argireline acetate has antiwrinkle and anti-aging activity .
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Cat. No.: HY-P5269
CAS No.: 887140-79-6
Target:  

Peptides

Research Areas:  

Metabolic Disease Endocrinology

Palmitoyl tetrapeptide-10 is a bioactive peptide. Palmitoyl tetrapeptide-10 works synergistically with other active ingredients to increase the expression of corneodesmosin (a marker of keratinocyte adhesion) and filaggrin (a marker of keratinocyte terminal differentiation), thereby reducing skin permeability and improving skin barrier function. Palmitoyl tetrapeptide-10 can be used in the research of sensitive skin syndrome and skin pigmentation .
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Cat. No.: HY-W131101
CAS No.: 26658-19-5
Sorbitan tristearate is a non-ionic surfactant, with a synergistic effect on skin permeability. Sorbitan tristearate can be used as an excipient, such as emulsifier. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
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Cat. No.: HY-P5107A
Synonyms: LMWP acetate; TDSP5 acetate
Target:  

VEGFR

Research Areas:  

Cancer

Low molecular weight protamine acetate (LMWP acetate;TDSP5 acetate) is a truncated arginine-rich protamine peptide, which also acts as an antidote for heparin/low molecular weight heparin and a cell-penetrating delivery vector. Low molecular weight protamine acetate neutralizes heparin-induced anticoagulant activities, including aPTT, anti-Xa and anti-IIa activities. Low molecular weight protamine acetate translocates across mammalian cell membranes, delivers conjugated impermeable molecules through tumor tissues, enhances the skin permeability of conjugated epidermal growth factor, and accelerates wound healing when conjugated with epidermal growth factor. Low molecular weight protamine acetate retains the in vitro cell proliferation activity of conjugated EGF, and also enables site-specific conjugation with peptides or proteins via genetic recombination. Low molecular weight protamine acetate can be used in studies related to colon cancer, skin wounds and diabetic skin wounds .
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Cat. No.: HY-149698
CAS No.: 2427043-61-4
Target:  

Tyrosinase

Research Areas:  

Cancer

Tyrosinase-IN-17 (Compound 5b) is a lipophilic, skin-permeable, and non-cytotoxic Tyrosinase inhibitor (pIC50=4.99). Tyrosinase-IN-17 can be used for research on melanin-related diseases, such as melanoma, melanogenesis, etc .
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Cat. No.: HY-B0568S
CAS No.: 1346601-82-8
Deferiprone-d3 is the deuterium labeled Deferiprone (HY-B0568). Deferiprone is a potent, orally active, brain-penetrant, cell-penetrant, skin-permeable, free iron chelating agent. Deferiprone inhibits the proliferation and migration, and stimulates apoptosis in tumor cell. Deferiprone can inhibit KDM. Deferiprone has antianemic, neuroprotective, anti-inflammatory, antioxidant, and antidotal activity. Deferiprone can be used in cancer, cardiovascular disease, infection, inflammation, and neurological disease study .
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Cat. No.: HY-157418
CAS No.: 1645269-61-9
Target:  

Endogenous Metabolite

Research Areas:  

Others

1-Deoxy-Cer is a Ceramide which is essential component of the skin permeability barrier.
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Cat. No.: HY-W009326R
CAS No.: 59227-89-3
Research Areas:  

Infection

Laurocapram is a chemical penetration enhancer that increases the permeability of compounds through the skin and mucous membranes, thereby improving their local or systemic efficacy. Laurocapram improves the skin permeability of a variety of hydrophilic and lipophilic compounds .
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Cat. No.: HY-144265
CAS No.: 2768626-06-6
Research Areas:  

Inflammation/Immunology

PDE4-IN-5 (compound 33a) is a potent and selective PDE4 inhibitor (IC50=3.1 nM). PDE4-IN-5 has favorable skin permeability and a well-characterized binding mechanism. Anti-psoriasis effect .
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Cat. No.: HY-W009326S
Laurocapram-15N is a deuterated labeled Laurocapram . Laurocapram is a chemical penetration enhancer that increases the permeability of compounds through the skin and mucous membranes, thereby improving their local or systemic efficacy. Laurocapram improves the skin permeability of a variety of hydrophilic and lipophilic compounds .
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Cat. No.: HY-161381
CAS No.: 3034837-89-0
PDE4-IN-15 (compound 7b-1) is an inhibitor of PDE4 (IC50 = 0.17 μM) and has anti-TNF-α activity (EC50 = 0.19 μM). PDE4-IN-15 has a good skin permeability .
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Cat. No.: HY-113819
CAS No.: 100-95-8
Synonyms: Dodecarbonium chloride
Research Areas:  

Infection

Metalkonium chloride (Dodecarbonium chloride) is a quaternary ammonium salt, surfactant, and transdermal penetration enhancer. Metalkonium chloride increases skin permeability to facilitate transdermal delivery. Metalkonium chloride enhances the growth inhibitory activity of Nystatin (HY-17409) ointment against C. monosa. Metalkonium chloride can be used in studies related to Candida monosa infections .
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