2768626-06-6
2768626-06-6
Chemical Structure
PDE4-IN-5
- CAS 番号: 2768626-06-6
- Formula:C21H28N2O3
- Molecular Weight:356.46
IUPAC Name: (2R,4S)-6-ethyl-2-(2-hydroxyethyl)-2,8-dimethyl-4-(2-methylprop-1-en-1-yl)-2,3,4,6-tetrahydro-5H-pyrano[3,2-c][1,8]naphthyridin-5-one
InChIKey: IOKJCBWLGAJZFW-VFNWGFHPSA-N
SMILES: O=C1N(C2=NC(C)=CC=C2C3=C1[C@@H](C[C@@](C)(O3)CCO)/C=C(C)\C)CC
Biological Activity: PDE4-IN-5 (compound 33a) is a potent and selective PDE4 inhibitor (IC50=3.1 nM). PDE4-IN-5 has favorable skin permeability and a well-characterized binding mechanism. Anti-psoriasis effect[1].
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PDE4-IN-5 | PDE4-IN-5 (compound 33a) is a potent and selective PDE4 inhibitor (IC50=3.1 nM). PDE4-IN-5 has favorable skin permeability and a well-characterized binding mechanism. Anti-psoriasis effect. | |||||||||||||||||||||
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