1. Peptides
  2. Argireline acetate

Argireline acetate (Synonyms: Acetyl hexapeptide-3 acetate)

Cat. No.: HY-P0033A
Handling Instructions

Argireline acetate (Acetyl hexapeptide-3 acetate) is a non-toxic, skin-permeable, antiwrinkle peptide. Argireline acetate significantly inhibits Ca2+ dependent neurotransmitter release (acetylcholine) at the neuromuscular junction. Argireline acetate has antiwrinkle and anti-aging activity.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Argireline acetate Chemical Structure

Argireline acetate Chemical Structure

Size Stock
100 mg   Get quote  
250 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Other In-stock Forms of Argireline acetate:

Other Forms of Argireline acetate:

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Argireline acetate (Acetyl hexapeptide-3 acetate) is a non-toxic, skin-permeable, antiwrinkle peptide. Argireline acetate significantly inhibits Ca2+ dependent neurotransmitter release (acetylcholine) at the neuromuscular junction. Argireline acetate has antiwrinkle and anti-aging activity[1][2][3].

In Vitro

The incubation of Argireline solution in different concentrations with human embryonic kidney HEK-293 (IC50 of 34.862 μM) and neuroblastoma IMR-32 cells (IC50 of 68.458 μM)) for 48 h have dose dependent antiproliferative effect. Argireline solution incubated in different concentrations with HSF has a dose-dependent antiproliferative effect on those cells. Cellular proliferation is not effected in Argireline low concentration[2].

In Vivo

Argireline is applied to the aged mice twice daily for 6 weeks. There is an improvement in the histological structure of skin tissue in the aged mice; the amount of type I collagen fibers increased, while that of type III collagen fibers decreased. Argireline could improve the histological structure of skin tissue and rejuvenate the aging skin[3].

Clinical Trial
Molecular Weight

949.04

Formula

C₃₆H₆₄N₁₄O₁₄S

Sequence

N-acetyl-Glu-Glu-Met-Gln-Arg-Arg-NH2

Sequence Shortening

Ac-EEMQRR-NH2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

ArgirelineAcetyl hexapeptide-3Acetyl hexapeptide3Acetyl hexapeptide 3OthersAntiwrinkleanti-agingnon-toxicskin-permeableneurotransmitterBoNTsshort-chainpeptideacetateInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Argireline acetate
Cat. No.:
HY-P0033A
Quantity:
MCE Japan Authorized Agent: