Tetrabenazine (Standard)
Tetrabenazine (Standard) is the analytical standard of Tetrabenazine (HY-B0590). This product is intended for research and analytical applications. Tetrabenazine (Ro 1-9569) is a brain-penetrant and orally active VMAT2-selective ligand with human VMAT2 Ki 100 nM. Tetrabenazine binds VMAT2 to block monoamine uptake into synaptic vesicles, potentiates cytoplasmic monoamine degradation. Tetrabenazine weakly blocks dopamine D2 receptors, and increases dopamine turnover via elevated cerebrospinal fluid homovanillic acid. Tetrabenazine can be used for the research of Huntington’s disease, tardive dyskinesia, and Tourette’s syndrome.
For research use only. We do not sell to patients.
- Purity : 98%
- CAS No.: 58-46-8
- Formula: C19H27NO3
- Molecular Weight:317.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
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Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 58-46-8
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Molecular Weight 317.43
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Formula C19H27NO3
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SMILES
O=C1[C@@H](CC(C)C)CN2CCC3=CC(OC)=C(OC)C=C3[C@]2([H])C1
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Synonyms
Ro 1-9569 (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Topics Synaptic Plasticity & Brain Health
Synaptic plasticity is the activity-, experience-, development-, and injury-dependent modification of synaptic strength, number, and structure, and it remains a central mechanism for learning, memory, sensory adaptation, and brain health.
2026-06-18
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Tetrabenazine (Standard) Related Classifications
HY-B0590R Related Classifications
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Keywords
- Tetrabenazine (Standard)
- 58-46-8
- Ro 1-9569 (Standard)
- Reference Standards
- Monoamine Transporter
- Dopamine Receptor
- substantia nigra
- monoamine
- Tourette’s syndrome
- rabbit blood platelets
- cerebrospinal fluid homovanillic acid
- striatal membranes
- human dopamine D2 receptor
- transgenic HD mouse model
- VMAT2
- Huntington’s disease
- Inhibitor
- inhibitor
- inhibit