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United States

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Cat. No.: HY-153978

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GLX481369

GLX481369 is a redox active substance. GLX481369 is a Nox4 inhibitor. GLX481369 has antioxidant effects.

For research use only. We do not sell to patients.

Formula: C₂₁H₂₄ClN₇O
Molecular Weight:425.91

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

GLX481369 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

GLX481369 is a redox active substance. GLX481369 is a Nox4 inhibitor. GLX481369 has antioxidant effects^[1].

All NADPH Oxidase Isoforms :

Chemical Information

Molecular Weight 425.91
Formula C₂₁H₂₄ClN₇O
SMILES

ClC1=CC(NC2=NC(N)=NC(CN3CCN(CC3)C4=CC=C(C=C4)O)=N2)=CC=C1C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Szekeres FLM, et al. A small molecule inhibitor of Nox2 and Nox4 improves contractile function after ischemia-reperfusion in the mouse heart. Sci Rep. 2021 Jun 7;11(1):11970. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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GLX481369

All NADPH Oxidase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

GLX481369 Related Classifications

HY-153978 Related Classifications