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Cat. No.: HY-160037

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SEW06622

SEW06622 is a BACE-1 inhibitor with an IC₅₀ value of 6.3 μM and can be used in Alzheimer's disease research.

For research use only. We do not sell to patients.

CAS No.: 261349-28-4
Formula: C₂₁H₂₆N₂O₂
Molecular Weight:338.44

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

SEW06622 Chemical Structure

CAS No.: 261349-28-4

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

SEW06622 is a BACE-1 inhibitor with an IC₅₀ value of 6.3 μM and can be used in Alzheimer's disease research^[1].

All Beta-secretase Isoforms :

BACE1
BACE2

Chemical Information

CAS No. 261349-28-4
Molecular Weight 338.44
Formula C₂₁H₂₆N₂O₂
SMILES

COC1=CC=CC(/C=N/C2CCN(CC2)CC3=CC=CC=C3)=C1OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Sharma P, et al. Design and development of multitarget-directed N-Benzylpiperidine analogs as potential candidates for the treatment of Alzheimer's disease. Eur J Med Chem. 2019 Apr 1;167:510-524. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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SEW06622

All Beta-secretase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

SEW06622 Related Classifications

HY-160037 Related Classifications