ZC0101
ZC0101 is a potent, orally active IDO1 and TrxR dual inhibitor with IC50 values of 0.084 μM and 7.98 μM, respectively. ZC0101 effectively induces apoptosis and ROS accumulation in cancer cells.
For research use only. We do not sell to patients.
- CAS No.: 2541604-52-6
- Formula: C17H15N3O2
- Molecular Weight:293.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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IDO1 0.084 μM (IC50) |
TrxR 7.98 μM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
0.55 μM
Compound: 41; ZC0101
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Cytotoxicity against human HCT-116 incubated for 24 hrs by CCK-8 assay
Cytotoxicity against human HCT-116 incubated for 24 hrs by CCK-8 assay
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[PMID: 35696861] |
Chemical Information
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CAS No. 2541604-52-6
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Molecular Weight 293.32
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Formula C17H15N3O2
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SMILES
O=C1C=CCCN1C(/C=C/C2=CC=CC=C2C3=CNC=N3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ZC0101 Related Classifications
HY-147772 Related Classifications
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