2541604-52-6
2541604-52-6
Chemical Structure
ZC0101
- CAS No.: 2541604-52-6
- Formula:C17H15N3O2
- Molecular Weight:293.32
IUPAC Name: (E)-1-(3-(2-(1H-imidazol-4-yl)phenyl)acryloyl)-5,6-dihydropyridin-2(1H)-one
InChIKey: JJOMQKGDGWAVKI-CMDGGOBGSA-N
SMILES: O=C1C=CCCN1C(/C=C/C2=CC=CC=C2C3=CNC=N3)=O
Biological Activity: ZC0101 is a potent, orally active IDO1 and TrxR dual inhibitor with IC50 values of 0.084 μM and 7.98 μM, respectively. ZC0101 effectively induces apoptosis and ROS accumulation in cancer cells[1].
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ZC0101 | ZC0101 is a potent, orally active IDO1 and TrxR dual inhibitor with IC50 values of 0.084 μM and 7.98 μM, respectively. ZC0101 effectively induces apoptosis and ROS accumulation in cancer cells. | |||||||||||||||||||||
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References
Keywords
