1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. α-L-Rhamnose

α-L-Rhamnose is a neutral sugar present in plants, animals, viruses and bacteria. α-L-Rhamnose is a ligand for α-L-rhamnose-recognizing lectin sites, trigger intracellular signaling pathways. α-L-Rhamnose induces rhaE and rhaA expression as a specific carbon source in Aspergillus nidulans, while glucose inhibits its cellular uptake. α-L-Rhamnose induces rapid and transient increases in intracellular free Ca2+ concentration in normal human dermal fibroblasts.

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α-L-Rhamnose

α-L-Rhamnose Chemical Structure

CAS No. : 6014-42-2

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Description

α-L-Rhamnose is a neutral sugar present in plants, animals, viruses and bacteria. α-L-Rhamnose is a ligand for α-L-rhamnose-recognizing lectin sites, trigger intracellular signaling pathways. α-L-Rhamnose induces rhaE and rhaA expression as a specific carbon source in Aspergillus nidulans, while glucose inhibits its cellular uptake. α-L-Rhamnose induces rapid and transient increases in intracellular free Ca2+ concentration in normal human dermal fibroblasts[1][2].

In Vitro

α-L-Rhamnose (10 μg/mL; ~15 minutes) triggers early, transient increases in intracellular free Ca2+ concentration in a subset of normal human dermal fibroblasts (NHDFs)[1].
α-L-Rhamnose (1% w/v; 1-24 h) induces rapid transcriptional upregulation of rhaE and rhaA in both Aspergillus nidulans wild-type and creAd30 derepressed strains, with greater transcript accumulation observed in the creAd30 strain[2].
α-L-Rhamnose (1% w/v; up to 48 h) is consumed by Aspergillus nidulans wild-type and creAd30 derepressed strains over 48 h, inducing extracellular α-L-rhamnosidase activity, while concurrent glucose presence blocks it uptake and enzyme activity in both strains[2].
α-L-Rhamnose (1% w/v; up to 30 h) is consumed by Aspergillus nidulans creAd30 derepressed strain over 30 h, inducing α-L-rhamnosidase activity, while concurrent ethanol presence does not block uptake but still prevents enzyme activity[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

164.16

Formula

C6H12O5

CAS No.
SMILES

O[C@H]1[C@@H]([C@@H]([C@H]([C@H](C)O1)O)O)O

Structure Classification
Initial Source

Aspergillus terreus

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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α-L-Rhamnose
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