α-L-Rhamnose
α-L-Rhamnose is a neutral sugar present in plants, animals, viruses and bacteria. α-L-Rhamnose is a ligand for α-L-rhamnose-recognizing lectin sites, trigger intracellular signaling pathways. α-L-Rhamnose induces rhaE and rhaA expression as a specific carbon source in Aspergillus nidulans, while glucose inhibits its cellular uptake. α-L-Rhamnose induces rapid and transient increases in intracellular free Ca2+ concentration in normal human dermal fibroblasts.
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- CAS No.: 6014-42-2
- Formula: C6H12O5
- Molecular Weight:164.16
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
α-L-Rhamnose (10 μg/mL; ~15 minutes) triggers early, transient increases in intracellular free Ca2+ concentration in a subset of normal human dermal fibroblasts (NHDFs)[1].
α-L-Rhamnose (1% w/v; 1-24 h) induces rapid transcriptional upregulation of rhaE and rhaA in both Aspergillus nidulans wild-type and creAd30 derepressed strains, with greater transcript accumulation observed in the creAd30 strain[2].
α-L-Rhamnose (1% w/v; up to 48 h) is consumed by Aspergillus nidulans wild-type and creAd30 derepressed strains over 48 h, inducing extracellular α-L-rhamnosidase activity, while concurrent glucose presence blocks it uptake and enzyme activity in both strains[2].
α-L-Rhamnose (1% w/v; up to 30 h) is consumed by Aspergillus nidulans creAd30 derepressed strain over 30 h, inducing α-L-rhamnosidase activity, while concurrent ethanol presence does not block uptake but still prevents enzyme activity[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 6014-42-2
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Molecular Weight 164.16
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Formula C6H12O5
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SMILES
O[C@H]1[C@@H]([C@@H]([C@H]([C@H](C)O1)O)O)O
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Structure Classification
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Initial Source
Aspergillus terreus
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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