6014-42-2
Chemical Structure
α-L-Rhamnose
- CAS No.: 6014-42-2
- Formula:C6H12O5
- Molecular Weight:164.16
IUPAC Name: (2R,3R,4R,5R,6S)-6-methyltetrahydro-2H-pyran-2,3,4,5-tetraol
InChIKey: SHZGCJCMOBCMKK-HGVZOGFYSA-N
SMILES: O[C@H]1[C@@H]([C@@H]([C@H]([C@H](C)O1)O)O)O
Biological Activity: α-L-Rhamnose is a neutral sugar present in plants, animals, viruses and bacteria. α-L-Rhamnose is a ligand for α-L-rhamnose-recognizing lectin sites, trigger intracellular signaling pathways. α-L-Rhamnose induces rhaE and rhaA expression as a specific carbon source in Aspergillus nidulans, while glucose inhibits its cellular uptake. α-L-Rhamnose induces rapid and transient increases in intracellular free Ca2+ concentration in normal human dermal fibroblasts[1][2].
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α-L-Rhamnose | α-L-Rhamnose is a neutral sugar present in plants, animals, viruses and bacteria. α-L-Rhamnose is a ligand for α-L-rhamnose-recognizing lectin sites, trigger intracellular signaling pathways. α-L-Rhamnose induces rhaE and rhaA expression as a specific carbon source in Aspergillus nidulans, while glucose inhibits its cellular uptake. α-L-Rhamnose induces rapid and transient increases in intracellular free Ca2+ concentration in normal human dermal fibroblasts. | |||||||||||||||||||||
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References
- [1]. Faury G, et, al. The alpha-L-Rhamnose recognizing lectin site of human dermal fibroblasts functions as a signal transducer: modulation of Ca2+ fluxes and gene expression. Biochim Biophys Acta. 2008 Dec;1780(12):1388-94. [Content Brief]
- [2]. Tamayo-Ramos JA, et al. L-rhamnose induction of Aspergillus nidulans α-L-rhamnosidase genes is glucose repressed via a CreA-independent mechanism acting at the level of inducer uptake. Microb Cell Fact. 2012 Feb 21;11:26.
