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19 Results for "
(+)-Ketoconazole
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "(+)-Ketoconazole" in MCE Product Catalog:
30
Ketoconazole (R-41400) is an imidazole anti-fungal agent, a CYP3A4 and CYP24A1 inhibitor.
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1 Cited Publications
Cat. No.: HY-B0105B
CAS No.: 142128-57-2
Synonyms: (-)-Ketoconazole; (-)-Ketoconazol; (-)-R 41400
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Levoketoconazole ((-)-Ketoconazole) is the 2S,4R enantiomer derived from racemic Ketoconazole (HY-B0105). Levoketoconazole is a potent and orally active cortisol synthesis inhibitor. Levoketoconazole inhibits key steps in cortisol and testosterone synthesis by inhibiting CYP11B1, CYP11A1, and CYP17A1. Levoketoconazole can be used for research on endogenous Cushing’s syndrome .
Cat. No.: HY-B0105A
CAS No.: 142128-59-4
Synonyms: (+)-Ketoconazol; (+)-R 41400
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(+)-Ketoconazole ((+)-R 41400) is an imidazole anti-fungal agent, a CYP3A4 inhibitor.
Cat. No.: HY-B0105R
CAS No.: 65277-42-1
Synonyms: Ketoconazol (Standard); R 41400 (Standard)
Ketoconazole (Standard) is the analytical standard of Ketoconazole. This product is intended for research and analytical applications. Ketoconazole (R-41400) is an imidazole anti-fungal agent, a CYP3A4 and CYP24A1 inhibitor.
Synonyms: N-DeacetylKetoconazole; R-39519
Deacylketoconazole (N-Deacetylketoconazole; R-39519) is an orally active metabolite of Ketoconazole (HY-B0105). Deacylketoconazole exhibits antifungal and antibacterial activity. Deacylketoconazole is cytotoxic in rats hepatocyte .
Cat. No.: HY-106542
CAS No.: 128326-82-9
Eberconazole is a dichlorinated imidazole derivative with antifungal activity. Eberconazole is more effective than Clotrimazole (HY-10882), Ketoconazole (HY-B0105), and Miconazole (HY-B0454). Eberconazole has potential for the study of dermatophytosis .
Eberconazole nitrate is a dichlorinated imidazole derivative with antifungal activity. Eberconazole nitrate is more effective than Clotrimazole (HY-10882), Ketoconazole (HY-B0105), and Miconazole (HY-B0454). Eberconazole nitrate has potential for the study of dermatophytosis .
Cat. No.: HY-B0105S1
CAS No.: 1398065-75-2
Synonyms: Ketoconazol-d4; R 41400-d4
Cat. No.: HY-B0105S
CAS No.: 1217706-96-1
Cat. No.: HY-B0105BS
CAS No.: 1217766-70-5
Synonyms: (-)-Ketoconazole-d3; (-)-Ketoconazol-d3; (-)-R 41400-d3
Cat. No.: HY-166670S
Synonyms: Ketoconazol-13C; R 41400-13C
Cat. No.: HY-W422288
CAS No.: 79156-75-5
Synonyms: (Rac)-Ketoconazol; (Rac)-R 41400
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(Rac)-Ketoconazole ((Rac)-R 41400) is an antifungal imidazole compound with oral activity. (Rac)-Ketoconazole interferes with ergosterol synthesis by inhibiting cytochrome P450-dependent 14α-sterol demethylase (CYP51), a key enzyme on the fungal cell membrane, leading to membrane dysfunction and ultimately inhibition of fungal growth and reproduction. (Rac)-Ketoconazole is indicated for studies of fungal infections .
Cat. No.: HY-137372A
CAS No.: 83374-59-8
Synonyms: trans-Ketoconazole; Ketoconazole impurity 4
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rel-trans-Ketoconazole (trans-Ketoconazole) is a drug impurity.
Cat. No.: HY-106542AR
CAS No.: 130104-32-4
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Eberconazole nitrate (Standard) is the analytical standard of Eberconazole nitrate. This product is intended for research and analytical applications. Eberconazole nitrate is a dichlorinated imidazole derivative with antifungal activity. Eberconazole nitrate is more effective than Clotrimazole (HY-10882), Ketoconazole (HY-B0105), and Miconazole (HY-B0454). Eberconazole nitrate has potential for the study of dermatophytosis .
Cat. No.: HY-W127933
CAS No.: 134071-44-6
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Ketoconazole impurity 6 is an impurity of Ketoconazole.
Cat. No.: HY-Z19683
CAS No.: 1392277-16-5
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Ketoconazole impurity 2 is an impurity of Ketoconazole.
Cat. No.: HY-Z7713
CAS No.: 1346598-39-7
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Ketoconazole impurity 5 is an impurity of Ketoconazole.
Cat. No.: HY-Z7717
CAS No.: 2095256-87-2
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Ketoconazole impurity 17 is an impurity of Ketoconazole (HY-B0105).
Cat. No.: HY-121057
CAS No.: 67739-71-3
Synonyms: 3-OH FNTZ
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3-Hydroxyflunitrazepam (3-OH FNTZ) is the major metabolite of Flunitrazepam (FNTZ), generated via 3-hydroxylation by CYP3A4 (Km = 286 μM), and represents the dominant metabolic pathway (>80%) in liver microsomes. Its formation is significantly inhibited by CYP3A4 inhibitors such as Ketoconazole (HY-B0105) (IC50 = 0.11 μM) and Ritonavir (HY-90001) (IC50 = 0.041 μM), indicating a strong dependence on CYP3A4 activity and potential drug interactions .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
