1. Cell Cycle/DNA Damage
    Apoptosis
    Immunology/Inflammation
    NF-κB
    Metabolic Enzyme/Protease
  2. DNA Alkylator/Crosslinker
    Apoptosis
    Reactive Oxygen Species
    Drug Metabolite
  3. 4-Hydroperoxy cyclophosphamide

4-Hydroperoxy cyclophosphamide 

Cat. No.: HY-117433
Handling Instructions

4-Hydroperoxy cyclophosphamide is the active metabolite form of the prodrug Cyclophosphamide. 4-Hydroperoxy cyclophosphamide crosslinks DNA and induces T cell apoptosis independent of death receptor activation, but activates mitochondrial death pathways through production of reactive oxygen species (ROS). 4-Hydroperoxy cyclophosphamide is used to treat lymphomas and autoimmune disorders.

For research use only. We do not sell to patients.

4-Hydroperoxy cyclophosphamide Chemical Structure

4-Hydroperoxy cyclophosphamide Chemical Structure

CAS No. : 39800-16-3

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Description

4-Hydroperoxy cyclophosphamide is the active metabolite form of the prodrug Cyclophosphamide. 4-Hydroperoxy cyclophosphamide crosslinks DNA and induces T cell apoptosis independent of death receptor activation, but activates mitochondrial death pathways through production of reactive oxygen species (ROS). 4-Hydroperoxy cyclophosphamide is used to treat lymphomas and autoimmune disorders.

Molecular Weight

293.08

Formula

C₇H₁₅Cl₂N₂O₄P

CAS No.

39800-16-3

SMILES

O=P1(OCCC(N1)OO)N(CCCl)CCCl

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

4-Hydroperoxy cyclophosphamideDNA Alkylator/CrosslinkerApoptosisReactive Oxygen SpeciesDrug MetaboliteInhibitorinhibitorinhibit

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4-Hydroperoxy cyclophosphamide
Cat. No.:
HY-117433
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