1. GPCR/G Protein
  2. Prostaglandin Receptor

Evatanepag (Synonyms: CP-533536 free acid)

Cat. No.: HY-14839 Purity: 98.02%
Handling Instructions

Evatanepag (CP-533536) is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation with EC50 of 0.3 nM.

For research use only. We do not sell to patients.

Evatanepag Chemical Structure

Evatanepag Chemical Structure

CAS No. : 223488-57-1

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 433 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
1 mg USD 180 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
5 mg USD 420 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
10 mg USD 600 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
50 mg USD 1800 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
100 mg USD 2520 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

Evatanepag (CP-533536) is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation with EC50 of 0.3 nM. IC50 value: 0.3 nM (EC50) Target PGE2 in vitro: CP-533536 is a potent and selective EP2agonist. CP-533536 demonstrates the ability to heal fractures when administered locally as a single dose in rat models of fracture healing. CP-533536 demonstrates excellent in vitro potency against EP2 and selectivity against a broad panel of other targets.

References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 2.1342 mL 10.6708 mL 21.3415 mL
5 mM 0.4268 mL 2.1342 mL 4.2683 mL
10 mM 0.2134 mL 1.0671 mL 2.1342 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

468.57

Formula

C₂₅H₂₈N₂O₅S

CAS No.

223488-57-1

SMILES

CC(C)(C)C(C=C1)=CC=C1CN(S(C2=CN=CC=C2)(=O)=O)CC3=CC(OCC(O)=O)=CC=C3

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: ≥ 32 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
Evatanepag
Cat. No.:
HY-14839
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